It can produce more severe impairment, and in more domains of life, than depression or anxiety.
它会比抑郁或者焦虑产生更严重的危害，并且危害到生活的其他方面。
Indications of severe impairment include blindness, hearing loss, cerebral palsy, and significantly delayed development.
严重损伤包括失明、听力丧失、大脑性瘫痪、明显发育迟缓。
It occurs when the eye cannot clearly focus the images from the outside world. The result of refractive errors is blurred vision, which is sometimes so severe that it causes visual impairment.
屈光不正是一种非常常见的眼部疾病，使眼睛无法对外界物体清晰地聚焦，而导致视力模糊，严重的时候可以引起视力损害。
These findings suggest that daily activity in patients with severe heart failure may not simply be limited by the failing heart, but also by an impairment in the leg muscles themselves.
这些发现说明，严重心脏衰竭患者的日常活动不仅仅是简单地受到心脏衰竭的限制，还受到腿部肌肉自身损伤的限制。
Haemorrhagic fever form: the symptoms of this form of the disease appear two to four days after the onset of illness, and begin with evidence of severe liver impairment, such as jaundice.
出血热症状：这种疾病症状在发病2至4天后出现，开始有严重肝损伤的迹象，比如黄疸。
After 15 years of diabetes, approximately 2% of people become blind, and about 10% develop severe visual impairment.
患糖尿病15年后，大约有2%的患者失明，10%左右的患者视力严重减退。
But with evidence mounting of troops returning home with severe neurological impairment, that attitude has finally changed.
但是越来越多的证据表明很多回家的士兵有严重的神经功能缺损，上述态度终于得以转变。
Many doctors believe drugs are being given too late, after symptoms are severe, so researchers more recently have started testing some in people with mild cognitive impairment.
很多医生都认为：当症状变得严重后用药已经很迟了，所以在目前，很多研究人员开始对部分人群进行精神认知缺陷的检测，以期能够提早预防阿氏病的发生。
The repeated strokes can lead to severe functional impairment or even death.
反复的中风可以引起严重的功能障碍甚至死亡。
Deaths have been reported in patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment and are treated with somatropin.
患严重肥胖或严重呼吸损伤的帕-魏二氏综合症，并使用生长激素治疗患者中，有死亡病例的报导。
In patients with renal artery stenosis or severe renal impairment, care should be exercised with dosing of EXFORGE.
对于肾动脉狭窄或严重肾功能损害患者，应注意Exforge剂量调整。
Alzheimer's disease (AD) is characterised by progressive memory loss and severe cognitive impairment.
阿尔茨海默氏病(老年痴呆症)以记忆逐渐衰退和严重的认知损害为特征。
Conclusions Elder patients with less education and longer course of disease have severe cognitive impairment.
结论年龄大、教育程度低、病程长的患者认知功能损害重。
Use cautiously in patients at risk for increased bleeding from trauma, surgery, or other pathologic conditions and in those with severe hepatic impairment.
对创伤，外科手术，或其他病理状态以及严重肝功能损害的患者慎用。
Conclusion tricuspid annular dilatation, right heart impairment and severe pulmonary hypertension are responsible for the development of late tricuspid regurgitation after mitral valve replacement.
结论二尖瓣置换术后远期三尖瓣功能性关闭不全与三尖瓣环扩大、右心功能损害和严重肺动脉高压有关，三尖瓣环扩大是其重要的原因。
CONCLUSION: DR leads to severe vision impairment among the diabetic residents.
结论：在糖尿病居民中，DR严重危害视力。
Care should be exercised with dosing of DIOVAN in patients with severe renal impairment.
对于严重肾功能损害患者，应注意Exforge剂量调整。
Regardless of the classification, the evidence suggests that impairment is often severe and few patients with bipolar disorder receive appropriate treatment.
有证据表明不管其分类，少数具有双向精神障碍的患者在接受了相同的治疗后常常受到严重的伤害。
The patients with severe renal impairment usually need to take dialysis.
对于严重肾功能损害的患者通常需要接受血液透析。
Nearly half of patients with advanced HIV infections have at least mild cognitive impairments, and about 5 percent have the severe form of cognitive impairment known as dementia.
近半的晚期艾滋病患者有轻度以上的认知损伤，有5%的患者有重度认知障碍。
A severe disorder of childhood characterized by withdrawal, preoccupation with fantasy, language impairment, and abnormal behavior, such as ritualistic acts and excessive object attachment.
一种发生于婴幼儿时期的严重心理紊乱，表现为内向、沉溺于奇怪的念头之中，语言能力较差，举动行为异常，如动作仪式化和过分喜爱某种物体。
Autism lies on the more severe end of the spectrum whereas Asperger's is a milder condition that doesn't involve speech impairment (as classic autism does);
自闭症位于谱系较为严重的一端；阿斯伯格综合症不包括语言障碍（而典型自闭症包括），是较为缓和的谱系障碍；
Dannewitz said the impairment is not so severe that it would warrant a driving ban in such individuals.
Dannewitz说，受损的不是那么严重，它会令在这样的个人中禁止驾驶。
Objective: To investigate the mechanism of stress glucosuria and renal function impairment in early stage of severe bum.
目的：通过对严重烧伤病人进行应激性糖尿症和早期肾功能损害等并发症观察研究，进一步了解其发病机制。
Choroid neovascularization (CNV) is one of the main reasons for many ocular diseases that can lead to severe visual impairment.
脉络膜新生血管是引起多种眼病视力下降、甚至致盲的主要原因之一。
You can have slightly elevated creatinine, but you shouldn't really have severe renal impairment.
肌酐轻度升高的患者可以用药，而严重肾功能损害的患者则应避免。
Cellular apoptosis might be the underlying mechanism of gut mucosal barrier impairment during severe infection.
细胞凋亡可能是严重感染时肠黏膜屏障破坏机制。
Zoledronic acid has not been studied in patients with severe renal impairment and is not recommended in this setting.
唑来膦酸还没有研究治疗重度肾功能损害，不建议在此设置。
After 15 years of diabetes approximately 2% of people become blind and about 10% develop severe visual impairment.
经过15年的糖尿病多年，大约2%的患者失明，10%左右的患者视力严峻受损。
After 15 years of diabetes approximately 2% of people become blind and about 10% develop severe visual impairment.
经过15年的糖尿病多年，大约2%的患者失明，10%左右的患者视力严峻受损。
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