• DNA damage of germ cells was assessed by single cell gel electrophoresis (SCGE or Comet assay).

    单细胞凝胶电泳(彗星实验)检测细胞DNA的损伤。

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  • Results: The main influential factors are the concentration of testee and its time of effect on the cell, the cell cycle in SCGE.

    结果:受试物的浓度及其对细胞的作用时间、细胞周期等是SCGE实验中的主要影响因素。

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  • Objective To explore the feasibility of alkaline single cell gel electrophoresis (SCGE) in biological dosimetry of ionizing radiation.

    目的初步探索碱性单细胞凝胶电泳(SCGE)方法用于电离辐射生物剂量估算的可行性。

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  • Methods The DNA damage induced by different concentrations of glycolaldehyde was detected using single cell gel electrophoresis assay (SCGE).

    方法采用单细胞凝胶电泳(SCGE)技术检测不同浓度乙醇醛对小鼠脾淋巴细胞DNA的损伤程度。

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  • The single cell gel electrophoresis(SCGE), also called comet assay, is a sensitive and rapid method for DNA damage detection in individual mammalian cell.

    前言:单细胞凝胶电泳是一种在单细胞水平检测哺乳类有核细胞DNA 断裂的新技术。

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  • Purpose and methods: Single cell gel electrophoresis (SCGE), sister chromatid exchanges (SCE), chromosome aberrations are three methods to determine DNA damage and repair.

    目的与方法:单细胞凝胶电泳技术(SCGE)、姐妹染色单体交换法(SCE)和染色体畸变分析法均能被用来检测dna的损伤或修复。

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  • SCGE reveals a great future in study of radiation biological dosimetry and has more ad-vantage than the other traditional methods, particularly at the early stage after radiation.

    尤其在照后早期,较其他传统生物剂量学技术具有明显优势,用于放射生物剂量学研究将有良好前景。

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  • After the survival cells were given second irradiation, both results of SCGE and micronucleus frequency showed that the second damage was correlated with the original irradiation doses.

    存活细胞经二次照射后,SCGE结果和微核发生率结果表明,首次照射剂量与子代二次照射后的损伤程度存在剂量效应关系。

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  • Objective To observe the consistency of DNA double-strand break between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis(SCGE).

    目的探讨整体照射与离体照射导致小鼠淋巴细胞DNA双链断裂的一致性,作为单细胞凝胶电泳技术应用于辐射生物剂量学的前期研究。

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  • Purpose and Methods: Using the alkaline single cell gel electrophoresis technique (SCGE) detect the DNA damage of lymphocytes in human peripheral blood, which were exposed to Sulfur mustard in vitro.

    目的与方法:利用碱性单细胞凝胶电泳(SCGE)技术在体外检测硫芥对人外周血淋巴细胞的损伤情况。

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  • Purpose and Methods: Using the alkaline single cell gel electrophoresis technique (SCGE) detect the DNA damage of lymphocytes in human peripheral blood, which were exposed to Sulfur mustard in vitro.

    目的与方法:利用碱性单细胞凝胶电泳(SCGE)技术在体外检测硫芥对人外周血淋巴细胞的损伤情况。

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