Some of the teens had changed to one particular gene—the glucocorticoid receptor (GR)—that helps regulate the body's hormonal response to stress.
一些青少年已经转换了一个特定的基因——糖皮质激素受体(GR)——帮助调节体内荷尔蒙对于压力的反应。
For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.
例如,糖皮质激素受体基因在大脑特定区域的持续表达提高了调节应激反应的能力。
By contrast, L-methionine increased the level of methylation and thus reduced the expression of the gene in animals with loving mothers, and led to fear, anxiety and a heightened response to stress.
与之相反,L -甲硫氨酸增加了甲基化水平,从而减弱了正常老鼠中糖皮质激素受体基因的表达,导致了恐惧、焦虑和对压力的强烈反应。
Early nurturing regulates the expression of a gene that is crucial to modulating the stress response.
提前培养调节基因表达对后期控制应激反应起到了重要作用。
"A detailed reading of that response, using gene expression data, reveals what type of pathogen the person is reacting to, " Zaas explained in a news release from the university.
泽滋在大学发表一则新闻中解释道:“仔细阅读反应,应用基因表达数据揭示与人起反应的病原型。”
He discovered that the activation of a gene called Toll is crucial for switching on the initial immune response that allowed his flies to fight off infection.
他发现Toll基因的激活对启动能帮助果蝇抵御感染的固有免疫反应尤为关键。
Of potential clinical importance: The gene expressed most often in breast-fed infants is involved in the cell's response to oxygen deprivation.
本研究得出的结论的临床价值:在婴儿哺乳过程中作用最显著的基因与细胞对缺氧的反应有关。
Taken together, these results suggest that glucocorticoid-receptor-gene methylation happens in the fetus in response to a mother's stress, and persists into adolescence.
总体看来,这些结论表明胎儿糖皮质激素受体基因的甲基化是由于母亲压力过大引起的,并且其影响将会持续到青春期。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。
In response to such incoming information, receptors on a cell's surface send signals to the nucleus that tweak gene expression and control cellular function.
细胞表面的受体对外界信息的相应反应就是将信息以信号的形式传递给启动基因表达和控制细胞功能的细胞核。
We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.
筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。
The major histocompatibility complex (MHC) is a gene cluster directly related to immune response.
主要组织相容性复合体(MHC)是和免疫反应直接相关的基因群。
AIM: to study the difference in gene expression of peripheral blood neutrophils between system inflammatory response syndrome (SIRS) patients and the health volunteers.
目的:研究全身炎症反应综合征患者外周血中性白细胞和健康人外周血中性白细胞的基因差异表达。
Objective: To explore the regulative mechanism of apoptosis-associated gene proteins on the adaptive response of splenocyte apoptosis in mice induced by low dose radiation .
目的:探讨低剂量辐射诱导小鼠脾脏细胞凋亡的适应性反应及其相关基因蛋白调控机制。
Response protein induced by drought already becomes a machine-made hot spot fighting drought to crop in studying adapting to arid adverse circumstances gene expression.
干旱诱导应答蛋白已成为抗旱研究中揭示作物适应干旱逆境基因表达机制的一个热点。
You might think that a gene involved in fighting infections must somehow enhance an animal's immune response.
你可能想到抗感染的基因肯定在一定程度上提高动物的免疫反应。
The gene expression of ET-1, ETAR, ETBR and ECE was evaluated by semi-quantitative reverse transcription polymerase chain response (RT-PCR).
采用半定量逆转录多聚酶链反应(RT - PCR)检测局部内皮素系统ET - 1、ETAR、ETBR及ECE的基因表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上,从而在转录水平上调节基因的表达。
The medicine contains a gene encoding an antigen that may be able to alert the immune system to the presence of foreign tissue, inducing a powerful immune response.
该药包含一种基因编码的抗原能够提醒免疫系统将肿瘤作为外来组织,从而诱导强烈的免疫反应。
All six ORC subunits are essential for initiation of DNA replication (1-3), and ORC may be involved in regulation of gene expression in response to stress (4).
ORC的六个亚基是DNA复制起始必不可少的(1 - 3),而且OR C可能参与应激响应过程中的基因表达(4)。
Objective: To explore the promoter position and existence of progesterone response element in HOXA11 gene cis-acting element.
目的:探讨hoxa11基因顺式作用元件是否存在启动子及孕激素应答元件序列。
Objective To sub-clone and express the gene encoding Schistosoma japonicum calcium-binding protein (SJE16) and study its immunological response.
目的亚克隆和表达日本血吸虫钙结合蛋白SjE16的编码基因,初步研究其免疫反应性。
There are many biological response paths in a cell, such as material metabolism paths, gene express paths, DNA duplication paths, signal transduction paths and so on.
细胞中有许多生物反应通路,比如物质代谢通路、基因表达通路、DNA复制通路、信号转导通路等等,其中最复杂的就是信号转导通路。
HLA is the most polymorphic gene complex of all human genetic systems, play a key role in specific immune response, determine the heterogeneity of individual associated with disease.
HLA是迄今所知最为复杂的遗传多态性系统,是调控人体特异性免疫应答和决定疾病易感性个体差异的主要基因系统。
The major histocompatibility complex( MHC) is a group of closely-linked gene, Which code the major histocompatibility antigen and play a critical role in immune response in vertebrate animals.
主要组织相容性复合体(MHC)是一群紧密连锁的基因,编码主要组织相容性抗原,在脊椎动物机体的免疫应答中具有重要作用。
Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.
目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。
These findings indicate that, in contrast to derivatives of ESCs, abnormal gene expression in some cells differentiated from iPSCs can induce T-cell-dependent immune response in syngeneic recipients.
这些发现说明,相对于胚胎干细胞的后代,从诱导多能干细胞分化来的某些细胞中异常的基因表达会在同基因的受体身上引起T细胞依赖的免疫反应。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
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