The drug, called rapamycin, was originally found in bacteria from Easter Island.
这种叫雷帕霉素的药最先是在复活节岛的一种细菌中找到的。
But the new study shows that rapamycin is still a useful tool for investigating aging.
但是新的研究表明雷帕霉素仍然是一个有效的研究衰老的工具。
However, because rapamycin depresses the immune system, it would have serious side effects for people with Parkinson's.
即便如此，因为雷帕霉素抑制了免疫系统，它对帕金森症患者有负面作用。
Previous research on rapamycin has hinted that it may have the power to extend human lifespan by more than a decade.
以前对雷帕霉素的研究为其也许可以把人的寿命延长十几岁提供了线索。
Mice on rapamycin, which was first discovered in soil fungus from Easter Island, lived about 10 per cent longer than other mice.
老鼠喂养的雷帕霉素，最开始是在复活岛上土壤中的真菌上发现的，这些吃雷帕霉素的老鼠比其他的老鼠生存的时间长10%。
When tested on nine-month-old mice, rapamycin had little effect.
对九个月大老鼠进行试验时，雷帕霉素作用甚微。
Furthermore, losartan can alleviate severe proteinuria induced by rapamycin.
氯沙坦可以减轻雷帕霉素所致的大量蛋白尿。
Methods SKOV3 cells were incubated with normoxia, hypoxia, and hypoxia plus rapamycin, respectively.
方法将SKOV3细胞分为常氧组、低氧组和低氧加雷帕霉素组。
The most commonly used anti-proliferative drugs are paclitaxel and rapamycin, and their derivatives.
目前最常用的抗增生药物为紫杉醇和雷帕霉素及其衍生物。
Current basic research suggests that rapamycin may be a very effective treatment for epilepsy in TSC.
研究结果建议，雷帕霉素可能是TSC癫痫症的一种非常有效的治疗。
The up-regulation of TRAIL might be related to the injury of vascular endothelial cells caused by rapamycin.
TRAIL表达上调与雷帕霉素诱导血管内皮细胞损伤有一定的相关性。
Objective To explore the effect of rapamycin in treatment of refractory chronic graft-versus-host-disease(cGVHD).
目的探索雷帕霉素在慢性移植物抗宿主病治疗中的作用。
Made by a type of soil bacterium, rapamycin has extended the life spans of yeast, flies and worms by about 25 percent.
雷帕霉素是用一种土壤细菌做成的，能将酵母、苍蝇和蠕虫的寿命延长约25%。
Objective: to study the effect of rapamycin on the biological characteristics of human hepatocellular carcinoma (HCC).
目的：探讨免疫抑制剂雷帕霉素对肝癌细胞生物学行为的影响。
Objective To evaluate the clinic effect of CYPHERTM (rapamycin) stent in treatment of bifurcation coronary artery lesion.
目的评价雷帕霉素涂层支架在冠状动脉分叉病变中的临床疗效。
And some researchers say there would be serious concerns in testing rapamycin, or any drug, in healthy people just to slow aging.
有些研究者说，仅仅为了延缓衰老而在健康的人身上试验雷帕霉素或其他任何药物，都会引起严重担忧。
Suppression of target of rapamycin, a downstream effector of phosphoinositide 3-kinase, also prevented lipofuscin accumulation in the heart.
雷帕霉素作用点（即为磷酸肌醇-3激酶基因下游的受动器）的抑制也同样能够阻止脂褐质在心肌的积聚。
AIM: To observe the mechanism that rapamycin (RPM) affects HMGB1 expression and release in RAW264.7 cells induced by lipopolysaccharides (LPS).
目的：探讨雷帕霉素抑制LPS诱导小鼠raw264.7细胞表达和释放HMGB1的作用机制。
Objective To investigate the effects of rapamycin on proliferation, levels of interleukin-2 (IL-2) and cell-cycle of mouse t lymphocytes in vitro.
目的研究雷帕霉素对小鼠t淋巴细胞体外的增殖、白细胞介素2 (IL - 2)表达及细胞周期的影响。
A commentary released with the rapamycin study strongly cautioned against taking the drug to prolong life because of potentially deadly side effects.
与雷帕霉素研究一起发布的一篇评论警告称，由于可能出现致命的副作用，不可服用雷帕霉素来延长寿命。
The drug is rapamycin, also called sirolimus, and is currently used as an immunosuppressant, to help prevent rejection of a new, transplanted kidney.
这种药物是瑞帕霉素，又被称为西罗莫司，目前被用于作为一种免疫抑制剂，有助于防止新移植肾脏发生排异。
The purpose of this article is to review the relevant preclinical and clinical data in the field of rapamycin eluting stent for the prevention of restenosis.
本文就目前雷帕霉素涂层支架在临床防治再狭窄研究的最新进展作一综述。
Methods 64 patients with bifurcation coronary artery lesion were randomly divided into rapamycin stent group and ordinary stent group, 32 cases in each group.
方法64例冠状动脉分叉病变患者随机分为两组，分别植入雷帕霉素涂层支架及普通支架，每组32例。
The 40 dogs that participated in the rapamycin trial, which just concluded its pilot run in Seattle, had to be at least 6 years old and weigh at least 40 pounds.
参与雷帕霉素试验的40只狗都是至少6岁，体重至少40磅。 这项研究刚在西雅图完成了初试阶段。
Dr Harrison and colleagues found that this was also the case with mice, and found that rapamycin feeding could extend mouse lifespan even when started late in life.
哈里森博士和他的同事发现这一点在小鼠身上也是如此。他们发现即使在小鼠老年时才开始喂食雷帕霉素，也能够延长小鼠的寿命。
Over 1,500 dog owners applied to participate in the trial of rapamycin, which has its roots in a series of studies in mice, the first of which was published in 2009.
1500多名狗主人申请参与雷帕霉素试验，这项试验基于一系列对小鼠做的研究，第一项研究结果发表于2009年。
In the competitive inhibition experiment, it showed that rapamycin and FK506 could bind this protein competitively and rapamycin had better binding capacity than FK506.
竞争性抑制实验显示雷帕霉素与FK506和该蛋白质的结合存在竞争性，且雷帕霉素与该蛋白质的结合能力比FK506强。
Scientists probably haven't stumbled on that drug yet, but a drug called rapamycin, already used to suppress the immune systems of organ transplant recipients, comes close.
科学家们可能还没发现那种不老药，但一种叫雷帕霉素的药物，已用来抑制器官移植受体的免疫系统，很接近。
Says Strong, "I think more immediately, people are starting to look at [rapamycin] for age-related diseases like Alzheimer's disease, Parkinson's disease or kidney disease."
斯特朗说，我相信很快就会有更多的人开始把雷帕霉素与年龄有关的诸如阿尔茨海默氏病、帕金森氏病、肾脏疾病联系起来。
Says Strong, "I think more immediately, people are starting to look at [rapamycin] for age-related diseases like Alzheimer's disease, Parkinson's disease or kidney disease."
斯特朗说，我相信很快就会有更多的人开始把雷帕霉素与年龄有关的诸如阿尔茨海默氏病、帕金森氏病、肾脏疾病联系起来。
应用推荐