Objective to determine the expression level of CD69 on CD4 + and CD8 + t cells in peripheral blood from children with rheumatoid arthritis (ra), and investigate their role in the pathogenesis of ra.
目的分析小儿类风湿关节炎(RA)患者的外周血cd4 +、CD 8 +T细胞CD 69表达水平,探讨其在小儿关节炎症发生过程中的免疫病理作用。
Conclusion: GRP peptide is epitopes of t cells in some RA patients.
结论:GRP肽是部分类风关患者关节内t细胞的T细胞表位。
Histopathologic features of RA encompass infiltration by macrophages and T cells synovial lining hyperplasia, neoangiogenesis, pannus formation and destruction of cartilage and bone.
其主要病理特点是滑膜细胞增生、衬里层增厚、多种炎性细胞浸润、血管翳形成,以及软骨和骨组织的破坏。
Based on both the importance of CD4 + t cells in the orchestration of rheumatoid inflammation and on promising results from animal models, anti-CD4 therapies were eagerly anticipated in ra.
鉴于CD 4 +T细胞在整个类风湿性炎症中的重要作用以及抗cd4疗法在动物模型中取得的预期结果,人们曾一度对应用抗cd4疗法治疗RA寄予厚望。
AIM: to investigate the fraction of CD4 + CD28-T cells and its correlation with lymphocytic apoptosis in peripheral blood of rheumatoid arthritis (ra) patients.
目的:研究类风湿关节炎(RA)患者外周血cd4 + CD 28 - T细胞比例与淋巴细胞凋亡异常的相关性。
AIM: To understand the relationship between T cell clonotypes and RA invasion through clonotypes of analysis of T cells accumulated in 4 feet joints of SKG mice.
目的:通过对类风湿性关节炎(RA)小鼠模型发病不同时期的四肢足关节聚集的T细胞克隆型的分析,了解T细胞克隆型与RA病变的关系。
Methods: T lymphocyte subsets in 11 patients with RA and 12 healthy controls were analyzed by using single and 2 color fluorescence flow cytometry.
方法:使用间接免疫荧光和直接免疫荧光方法对11例RA患者和12例健康人的外周血T淋巴细胞进行了研究。
Methods: T lymphocyte subsets in 11 patients with RA and 12 healthy controls were analyzed by using single and 2 color fluorescence flow cytometry.
方法:使用间接免疫荧光和直接免疫荧光方法对11例RA患者和12例健康人的外周血T淋巴细胞进行了研究。
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