PTTG mRNA in the pituitary glands was regulated by estradiol, with possible involvement in estradiol induced tumorigenesis in rats.
垂体瘤转化基因参与调节雌激素诱导的大鼠垂体腺瘤发生。
Methods: Transfect plasmid which carries PTTG gene use liposome, constructs the pituitary cell line which high express PTTG gene, observe the cell form.
方法：用脂质体转染携带PTTG基因的表达质粒，构建过表达PTTG基因的垂体细胞株，观察细胞形态。
Conclusion: (1) High expressed the PTTG gene in the normal pituitary gland cell also to be possible to cause the cell cancer, enhancement attack ability.
结论：(1)在正常垂体细胞中过表达PTTG基因也可以引起细胞癌变，增强侵袭能力。
Objective To explore the expression of PTTG gene of chronic myeloid leukemia(CML)in different phases for providing information about the potential mechanisms of CML.
目的研究垂体瘤转化基因（PTTG）在慢性粒性细胞白血病（CML）患者中不同临床阶段的基因表达，为阐明CML演变的可能机制提供依据。
Objective: The aim of this study was to explore expression of pituitary tumor transforming gene (PTTG) in estrogen-induced pituitary tumorigenesis in rats, to investigate its role in this process.
目的：研究垂体瘤转化基因在实验大鼠垂体腺瘤组织中的表达规律，探讨垂体瘤转化基因在垂体腺瘤形成过程中的作用。
Objective: The aim of this study was to explore expression of pituitary tumor transforming gene (PTTG) in estrogen-induced pituitary tumorigenesis in rats, to investigate its role in this process.
目的：研究垂体瘤转化基因在实验大鼠垂体腺瘤组织中的表达规律，探讨垂体瘤转化基因在垂体腺瘤形成过程中的作用。
应用推荐