A foundation for studying protein design using the HNP model and the relative entropy was made.
该工作为基于相对熵及HNP模型的蛋白质设计研究打下了基础。
A new contact intensity function is given to consist with protein design research based on the relative entropy.
为了与基于相对熵方法的蛋白质设计工作进行统一,采用了新的接触强度函数。
Protein folding and protein design has become one of the most actively studied problems in modern molecular biology.
蛋白质折叠和蛋白质设计的研究是当代分子生物学的热点问题,具有重要的科学意义。
If all goes well, the game will move on to protein design this summer, by including options that allow players to modify sections of the protein.
如果进展顺利,今年夏天这款游戏就能拓展至蛋白质设计,玩家可以调整蛋白质片段来设计出需要的特定蛋白。
Denovo protein design is not only the most rigorous check for our knowledge on protein folding, but also a significant way to get new information.
从理论上来说,蛋白质全新设计不仅是对蛋白质折叠知识进行最严格的检验,而且是进一步获取新知识的重要途径。
Better resolution is important for a number of applications, including but not limited to virtual screening of drug targets with docking procedures and protein design.
好的蛋白结构分辨率对于对于很多应用都是非常重要的,包括但不限于虚拟筛选药物靶点与对接程序和蛋白质设计。
Structural bioinformatics based rational protein design will play important role in biological research and development of protein therapeutics in the post genome era.
利用结构生物信息学方法进行蛋白质的理性设计,将会在后基因组时代的生物学研究和蛋白药物开发中起到越来越重要的作用。
The next step in this direction is to design more new tRNAs that can incorporate more unnatural amino acids into protein chains.
该研究的下一步是设计更多的新的转运RNA,使得更多的非常规氨基酸能够被携带参与蛋白链的合成。
But there are still major limitations on the design and implementation of engineered protein-based therapies.
但是,在以工程化的蛋白为基础的疗法的设计和干预方面仍然存在大的障碍。
Lapatinib is a product of the growing field of molecular medicine-the design of drugs to attack specific protein molecules associated with particular diseases.
Lapatinib是一种分子药物市场蓬勃发展的产品——被设计用来靶向治疗与疾病相关的特定的蛋白质分子。
Protein models are also used for phasing of crystallographic data and, in some cases, for drug design.
蛋白质模型也被用于定相结晶数据,及在某些情况下,进行药物设计。
The complex structure of protein and its ligand is important for clarifying the function and action mechanisms of protein and useful for drug design.
研究蛋白质与相应配体分子复合物的结构及配体与蛋白质的相互作用对阐明蛋白质的结构、功能、作用机制和药物设计具有重要的指导意义。
BACKGROUND: the protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease.
背景:疾病相关蛋白质的蛋白质结构对进行抗一种特定疾病的基于结构的药物设计是重要的。
The basic theory of molecular docking design was first briefly described, and then the concept of the key residues in the protein receptor was introduced to establish a new flexible docking model.
首先阐述了分子对接设计的基本原理,然后在蛋白质受体中引入关键残基的概念,建立了一个新的柔性分子对接模型。
This paper briefly introduced the features of soybean protein wastewater, analyzed the process design and the running of two engineering.
介绍了两公司大豆蛋白废水的水质水量和性质特征,分析工程的工艺设计和调试运行状况。
This score enables ranking of different DNA binding sites given a protein binding site and vice versa and can be used in molecular design protocols.
这评分使排名不同的DNA结合位点提供的蛋白质结合位点,反之亦然,可以用于分子设计议定书。
Then according to experiment design, the effects of rChIL-18 protein refolding yield at different densities were investigated by the systems of artificial chaperone at different densities.
然后按照试验设计,考察不同浓度组成的人工分子伴侣体系对不同浓度鸡IL-18重组蛋白复性率的影响。
The readers are well introduced to the theoretical basis of manufacturing powdered milk enriched with protein, its ingredient recipe design and its production run.
文章较详细地介绍了营养蛋白奶粉生产的理论依据、配方设计及生产过程。
Its goal is "… to develop methods that accurately predict and design protein structures and complexes, an endeavor that may ultimately help researchers develop cures for human diseases."
该项目的目标是“寻找能够准确预测和设计蛋白质结构及聚合物的方法,希望能最终帮助研究者们找到治愈人类疾病的途径”。
We hope that the scientific community can use this new knowledge to help design new drugs that will bind selectively to the defective protein to protect the body from its damaging effects.
我们希望,科学界可以使用这个新的知识,以帮助设计新的药物,将选择有缺陷的蛋白质结合,以保护身体的破坏性影响。
An orthogonal regression design is used in studying the preparation of fermentation rice juice beverage from high-protein rice flour and broken rice.
以清洁米加工的副产品高蛋白米粉和碎米为原料,采用回归正交设计法研制发酵米汁饮料。
Identification of protein-protein interaction sites is essential for the mutant design and prediction of protein-protein networks.
蛋白质相互作用位点的识别对于突变设计和预测蛋白质相互作用的网络是非常重要的。
For an AIDS vaccine design, we use these antibodies identified a protein vaccine to keep the part, removed unnecessary part of the immune system can focus on related structures.
对于艾滋病疫苗设计而言,我们使用这些抗体发现了疫苗要保留的蛋白质的部分,去除了不必要的部分,让免疫系统可以把重点放在相关结构上。
Prediction of protein-protein interaction sites is essential for mutant design and reconstruction of protein-protein interaction networks.
蛋白质相互作用位点的预测对于突变设计和蛋白质相互作用网络的重构都是至关重要的。
G-protein Coupled Receptors (GPCRs) belong to one of the largest superfamilies of membrane proteins and are important targets for drug design.
蛋白偶联受体属于跨膜蛋白的大家族,在药物设计中起着很重要的作用。
The purpose was to provide simple, robust, easy to implement and feasible approaches for drug-protein binding study in new drug design and therapeutic drug monitoring (TDM).
其目的是为新药研究和治疗药物监测中研究药物-蛋白结合作用提供简单、耐用、易操作和可行的方法。
The purpose was to provide simple, robust, easy to implement and feasible approaches for drug-protein binding study in new drug design and therapeutic drug monitoring (TDM).
其目的是为新药研究和治疗药物监测中研究药物-蛋白结合作用提供简单、耐用、易操作和可行的方法。
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