• A general protein conformation searching and genetic algorithms are briefly introduced first.

    首先简要介绍了遗传算法一般蛋白质构象搜索问题

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  • Fluorescence spectroscopy is an effective method of study on protein conformation in aqueous solution.

    萤光光谱法研究蛋白质水溶液分子构象一种有效方法

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  • Proline-directed phosphorylation sites like this one are often targeted by CDKs and MAPKs and can often dramatically affect protein conformation (4,5).

    类似这种的氨酸导向的磷酸化位点通常是CDKsMAPKs的靶标,并往往显著影响蛋白质的构象(4,5)。

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  • This paper presents a fast exhaustive search algorithm in order to search the protein conformation space based on the lattice model by constructing a directional binary tree.

    本文构造具有方向导向性的完全二叉树的基础,提出了一种适合研究蛋白质构象格子模型快速穷举搜索算法

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  • This three-dimensional conformation is held together by the interactions of the amino acids at different parts of the polypeptide chain with each other, and determines the activity of the protein.

    这种三维构造通过不同部位氨基酸连在一起决定了蛋白活性

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  • This does not disturb the conformation of the protein molecules; but those in state "zero" absorb light at this wavelength.

    不会干扰蛋白质分子构造那些0状态的蛋白质分子将吸收这个波长

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  • Objective To determine the characteristic conformation of Staphylococal protein A-gold.

    目的确定葡萄球菌蛋白a胶体金分子特征性构象

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  • Recently, it has been proved that an mRNA molecule instructs the corresponding protein synthesizing not only in the primary structure but also in the conformation.

    最近研究表明信使RNA蛋白质合成中,不但表现出维序列上对应,且在两者的空间构象上表现出某些对应关系。

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  • Modification of a protein usually refers to physical, chemical, or enzymatic treatments changing its conformation and structure and consequently its physicochemical and functional properties.

    蛋白质改性的是用物理化学酶法改变蛋白质的构象结构从而改变理化性质。

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  • Therefore the conformation of protein can change and even the protein can be inactivated in the process of adsorption.

    因此蛋白质吸附过程中,构象发生变化,甚至导致失活

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  • In their structural studies, those scientists had found only the active conformation of EGFR in their protein crystals.

    他们结构研究中,这些科学家已经发现,在他们制备的蛋白质晶体中存在活性构象EGFR

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  • Antifreeze proteins are a kind of protein inhibiting the growth of ice crystals and modifying the conformation of ice crystals, conferring freeze resistance to biology without temperature modulation.

    抗冻蛋白一类抑制冰晶生长修饰冰晶形态蛋白质,赋予体温调节能力的生物在低温的环境里得以生存。

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  • CONCLUSION Penetration enhancers can change the fluidity of membrane lipid and the conformation of membrane protein in certain degrees, and increase the sublingual absorption of insulin.

    结论渗透促进剂可以不同程度地影响流动性蛋白构象提高胰岛素舌下给药后降糖效果。

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  • CONCLUSION the stability of the protein during spray drying was affected by crystallization, surface adsorption and conformation transformation.

    结论蛋白质喷雾干燥过程中的稳定性载体结晶表面富集构象变化等多种机制影响。

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  • BACKGROUND: the properties, integration mechanism and conformation change of protein are closely related with the biological effects of nanocomposites.

    摘要:背景纳米生物复合材料性质、形成机制蛋白质构象变化与其生物学效应密切相关

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  • Protein secondary structure prediction becomes the most important step of predicting the space conformation from protein molecule.

    蛋白质二级结构预测是蛋白质结构预测重要组成部分,是蛋白质结构预测关键步骤

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  • Protein secondary structure prediction becomes the most important step of predicting the space conformation from protein molecule.

    蛋白质二级结构预测是蛋白质结构预测重要组成部分,是蛋白质结构预测关键步骤

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