Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter (BCP) mutation.
目的了解拉米夫定耐药与HBV基因型及HBV基本核心启动子(BCP)突变之间的关系。
The reporter gene was used to study the mutation influencing the activity of promoter.
对发现的突变，进行荧光素酶报告基因瞬时表达研究。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达，但并不是通过基因突变或促进子甲基化而实现的，因此其失表达的机制还不清楚。
Therefore mutation of insulin gene promoter might not be a major genetic factor for type 2 diabetes mellitus in Chinese patients.
结论：胰岛素基因启动子突变可能不是中国人2型糖尿病的重要遗传因素。
The mutation of ERG11 promoter may be associated with the resistance of C. albicans to fluconazole.
ERG11基因启动子突变可能与白念珠菌对氟康唑耐药有关。
The mutation of ERG11 promoter may be associated with the resistance of C. albicans to fluconazole.
ERG11基因启动子突变可能与白念珠菌对氟康唑耐药有关。
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