This complex is also a key component of the pre-replication complex (pre-RC) (reviewed in 1).
该复合体也是前复制复合体(pre - RC)的关键组成部分(回顾1)。
The MCM complex is thought to be the replicative helicase, and formation of the pre-RC is referred to as chromatin licensing.
MCM复合体被认为是一种复制解旋酶,而pre-RC的形成参与染色质许可。
MCM proteins are removed during DNA replication, causing chromatin to become unlicensed through inhibition of pre-RC reformation.
DNA复制时m CM蛋白被清除,通过pre - RC重构的抑制引起染色质未识别化。
The prereplication complex (Pre-RC) forms in late mitosis/early G1 phase beginning with the binding of CDT1 and cdc6 to the origin, which allows binding of the heterohexameric MCM2-7 complex.
前复制复合体(Pre-RC)在有丝分裂末期/G1早期随着CDT1和cdc6的结合而形成,允许异源六聚化的MCM2-7复合体的结合。
The pre-replication complex (Pre-RC) forms in late mitosis/early G1 phase beginning with the binding of CDT1 and cdc6 to the origin, which allows binding of the heterohexameric MCM2-7 complex.
前复制复合体(Pre-RC)在有丝分裂末期/G1早期随着CDT1和cdc6的结合而形成,允许异源六聚化的MCM2-7复合体的结合。
The pre-replication complex (Pre-RC) forms in late mitosis/early G1 phase beginning with the binding of CDT1 and cdc6 to the origin, which allows binding of the heterohexameric MCM2-7 complex.
前复制复合体(Pre-RC)在有丝分裂末期/G1早期随着CDT1和cdc6的结合而形成,允许异源六聚化的MCM2-7复合体的结合。
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