The expression of PI3K protein was located in cytoplasm and (or) nucleus.
PI 3k蛋白表达主要定位于细胞质和(或)胞核。
However, interfering with PI3K signaling might increase the risk of bacterial infections in humans.
但是干扰PI 3 K信号通路可能会增加患者细菌感染的机会。
Objective To investigate the roles of PI3K pathway in multicellular resistance of lung adenocarcinoma A549 cells.
目的探讨PI3K信号通路在肿瘤群集耐药中的作用。
Previous data showed that NOK could activate the phosphatidylinositol 3 -kinase (PI3K) pathway in stable BaF3 cells.
前期的研究表明,NOK在小鼠前B细胞(BaF3)中能够激活磷脂酰肌醇3-激酶(PI3K)信号通路。
PI3K becomes the focus on the effects of cell growth and cell proliferation by nutrition uptaking and cell cycle regulation.
PI3K调控细胞周期、参与营养物质的摄取,进而具有影响细胞的生长和分化等多方面功能,备受瞩目。
They also contend in their patent application that suppressing PI3K will increase feeding in farmed animals and reduce feed waste.
他们在专利中还主张抑制PI3K还可以提高饲养动物的摄食量和减少食物浪费。
Conclusions FAK and PI3K signal pathway induced by OPN should participate in invasion and metastasis of later carcinoma of large intestine.
结论O PN诱导的FAK和PI 3 K信号途径参与了大肠癌中晚期发生的侵袭与转移过程。
Conclusion the PI3K signal pathway may be involved in AHR and the airway remodeling through promoting airway smooth muscle cells proliferation in asthma.
结论PI 3 K信号通路可能通过促进气道平滑肌细胞增殖参与哮喘气道高反应性及气道重构过程。
The PI3K deltainhibitor idelalisib (Zydelig) and the BTK inhibitor ibrutinib (Imbruvica) have shown promise for patients with relapsed follicular lymphoma.
PI3K抑制剂idelalisib和BTK抑制剂ibrutinib对复发的滤泡性淋巴瘤显示出很好的潜力。
This data complements Drosophila genetics studies suggesting the possible involvement of the tuberin-hamartin complex in the PI3K/Akt mediated insulin pathway (8-10).
这些数据和果蝇(Drosophila)遗传学研究表明tuberin-hamartin 复合物可能在PI3K/AKT介导的胰岛素通路中取作用(8-10)。
The present data indicate that exogenous applications of low quantities of PAF induce a cardioprotective effect, through PI3K and PKC activation, similar to that afforded by IP.
本研究显示外源性使用低剂量的PAF可产生心脏保护作用,主要是通过活化pi3k和PKC来实现的,同样IP也可产生相似结果。
Conclusion: Both spinal and supraspinal neuronal Phosphoinositide 3-kinase (PI3K) pathway played important role in morphine dependent and naloxone-precipitated withdrawal response in mice.
结论:脊髓和脊髓上中枢神经元pi - 3 K信号通路均参与吗啡依赖的形成及戒断反应的表达。
In the study conducted using a fruit fly, they found that negative feedback mediated by PI3K regulates the excitability of neurons, an issue in a number of ailments that include neurofibromatosis.
在用果蝇的实验中,研究人员发现由PI3K介导的负反馈可以调节神经的兴奋性,这个问题在包括神经纤维瘤等许多疾病中存在。
For example, scientists could develop a drug to prevent BAD from being inhibited. Or, they could use the findings to test current drugs designed to block the effects of PI3K, one of the molecules.
例如,科学家能够开发一种预防BAD被抑制的药物,或者他们用这些发现来检验当前设计来用于阻止其中一种分子如磷酸肌醇3 -激酶发挥效应的药品。
For example, scientists could develop a drug to prevent BAD from being inhibited. Or, they could use the findings to test current drugs designed to block the effects of PI3K, one of the molecules.
例如,科学家能够开发一种预防BAD被抑制的药物,或者他们用这些发现来检验当前设计来用于阻止其中一种分子如磷酸肌醇3 -激酶发挥效应的药品。
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