Syntheses and properties of PLA-PEG block copolymers were introduced, and their applications for micelles, microspheres and nanoparticles in drug delivery system were also reviewed.
介绍PLA -PEG嵌段共聚物的合成和性质,综述其作为胶束、微球、纳米粒等的载体在药物释放系统中的应用。
Recently, poly (d, l-lactide) -poly (ethylene glycol) (PLA-PEG) block copolymers have been widely applied owing to the favorable biodegradability and biocompatibility.
聚乳酸-聚乙二醇嵌段共聚物因具备良好的生物可降解性和相容性而得到广泛应用。
This article reviewed pharmaceutical research and application of biodegradable PEG-PLA block copolymers and its micro - or nano-particles as drug delivery system.
综述可生物降解嵌段共聚物聚乙二醇-聚乳酸(PEG -pla)及其微粒给药系统在药剂学中的研究与应用。
At present, block copolymers containing PCL and PEG chains are mainly prepared by active ionic polymerization using traditional chemical catalysts, some toxic organometallic compounds.
然而,两亲嵌段共聚物的传统的制备方法是有机金属催化剂催化的活性离子聚合法,故产物中难免会残留有毒的有机金属催化剂。
The microspheres of PEG-PLA block copolymers can enhance the stability of protein and polypeptide, and profit the release of poorly water-soluble pharmaceuticals.
该嵌段共聚物微球能提高蛋白、多肽的稳定性,有利于难溶性药物释放。
The microspheres of PEG-PLA block copolymers can enhance the stability of protein and polypeptide, and profit the release of poorly water-soluble pharmaceuticals.
该嵌段共聚物微球能提高蛋白、多肽的稳定性,有利于难溶性药物释放。
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