Statins increase human serum levels of PCSK9.
他汀类药物可以升高血pcsk9水平。
"You want more LDL receptors, so blocking PCSK9 is a good thing," says Horton.
“您想要更多的低密度脂蛋白受体，使阻塞pcsk9是一件好事，说：”霍顿。
PCSK9 binds to LDL receptors on the surface of liver cells and causes those receptors to break down.
pcsk9结合低密度脂蛋白受体表面上的肝细胞和原因，这些受体打破。
Mice that lack the PCSK9 gene have lower levels of cholesterol, and people with an ineffective form of the PCSK9 gene have lower levels of LDL and a dramatically lower risk of heart disease.
小鼠缺乏pcsk9基因有水平较低的胆固醇，和人民同一个无效形式的pcsk9基因有水平较低的低密度脂蛋白和显着降低罹患心脏病的风险。
Mice that lack the PCSK9 gene have lower levels of cholesterol, and people with an ineffective form of the PCSK9 gene have lower levels of LDL and a dramatically lower risk of heart disease.
小鼠缺乏pcsk9基因有水平较低的胆固醇，和人民同一个无效形式的pcsk9基因有水平较低的低密度脂蛋白和显着降低罹患心脏病的风险。
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