Aim To investigate the effects of lipophilic fraction of Ganoderma lucidum on PC12 differentiation.
目的研究灵芝酯溶性提取物对PC12细胞分化的影响。
Objective To decide whether the extracellular signal-regulated kinase (ERK) play a crucial role in PC12 differentiation induced by nerve-growth factor (NGF).
目的探讨细胞外信号调节激酶(ERK)在NGF诱导的PC12细胞分化中的作用机制。
AIM: To study the effects of marrow stromal cells conditioned medium (CM) on proliferation and differentiation of PC12 cells, meanwhile whether CM can protect PC12 cell from the damage of rotenone.
目的:观察骨髓基质细胞条件液对PC 12细胞生长与分化的影响,分析其能否保护PC 12细胞免受鱼藤酮的毒性作用。
Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.
目的:利用NGF诱导的PC12细胞分化模型,探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。
NECL2 distributed in cell body and protuberance of primary culture neuron. The rat adrenal gland tumor cell line PC12 can be induced into neuronal differentiation.
大鼠肾上腺嗜铬细胞瘤细胞PC12具有神经元样分化的潜能,在PC12细胞中转染并过量表达NECL2能够诱导细胞发生神经元样分化。
The screening results showed that most of polysaccharide fractions induced the differentiation of PC12 cell.
PC12细胞实验结果表明,多个多糖组分能刺激PC12细胞产生神经纤维样突起。
The screening results showed that most of polysaccharide fractions induced the differentiation of PC12 cell.
PC12细胞实验结果表明,多个多糖组分能刺激PC12细胞产生神经纤维样突起。
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