The rate of p16 expression markedly reduced with the increase of clinical stages.
可见p16基因蛋白的阳性表达率随着临床分期升高呈明显下降趋势。
Results: The results showed that P16 expression was lower in thyroid adenomas than that in thyroid adenocarcinomas (p<0. 01).
结果：甲状腺癌P16蛋白表达量明显低于甲状腺腺瘤（P＜0。01）；
P27 and P16 proteins expression is of some guiding significance in histologic grade, malignant development and prognostic assessment for chondrosarcoma.
P 27和P 16蛋白表达对软骨肉瘤组织学分级，恶性进展和预后判断有指导意义。
Objective: to determine the expression of CDK4 and P16 and its relation to the clinicopathological characteristics in some epidermal tumors.
目的：探讨CDK4、P 16在某些表皮肿瘤中的表达及其与临床病理特征的关系。
Objective To study the expression of P63 and P53, the relation between the expression of P63, P53 and PCNA, P16 in pancreatic neoplasms.
目的研究P53、P 63基因在胰腺肿瘤中的表达及其意义；P 63基因表达与P 53、增殖细胞核抗原(pcna)、P 16表达的关系及其意义。
Objective: to detect the expression of P16 and MDM2 in gastric tumors (including both benign and malignant ones), and explore their relationship in the cell apoptosis of gastric carcinoma.
目的：检测胃肿瘤及正常胃组织中P 16与MDM2的表达，探讨其在肿瘤凋亡中的相互关系。
Conclusions:In the study, we can conclude that the years of smoking, eat fat meat and family carcinoma history are the risk factors of P16 abnormal expression in CRC.
结论：在暴露于危险因素至癌变过程中，P16基因表达缺失可能与吸烟年数、好吃肥肉、癌家族史危险因素有关。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达，了解其在翼状胬肉发病机制中的作用。
Methods The P16 gene modification and PCNA protein expression were detected in 41 brain glioma specimen with different grades and 7 normal brain tissue specimen.
方法检测41例不同级别脑胶质瘤标本和7例正常脑组织P16基因改变和PCNA蛋白表达情况。
Objective to investigate the relationship between the expression of P16 and P53 in brain astrocytoma with their grading of pathological histology.
目的探讨P 16和P 53蛋白的表达与脑星形细胞瘤的病理组织学分级的关系。
Objective:To study the expression of P16 protein and PCNA in ampullary carcinoma and its relation with its pathological features.
目的：探讨壶腹癌中抑癌基因P16蛋白与增殖细胞核抗原（PCNA）表达的相关性及其与肿瘤临床病理特征的关系。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
Conclusions The expression of VEGF, P53, and P16 was correlated with glioma malignant degree.
结论VEGF、P 53、P16在胶质瘤中的表达与其恶性程度相关。
CONCLUSIONS: positive and strongly positive expression of P16 in ca tissue implied risk of cancerization of ca.
结论：尖锐湿疣患者P 16蛋白阳性或强阳性表达提示有癌变的可能。
Objective: to explore the risk factors of P16 protein abnormal expression in colorectal cancer (CRC).
目的：探讨大肠癌p 16基因异常表达的危险因素。
Conclusion: the expression of P16 protein is related to the degree of the differentiation but not related to the size of the humors.
结论：提示P16蛋白的表达与肝细胞性肝癌的分化程度有关，与肿瘤大小有关。
Aim: to study the expression of P16 in tissues of primary hepatocellular carcinoma (HCC).
目的；探讨原发性肝癌(HCC)中P 16蛋白的表达。
Objective: To investigate the expression of P16 protein in premalignant lesions and gastric carcinoma, including dysplastic gastric mucosa and intestinal metaplasia in gastric mucosa.
目的：研究p 16蛋白在胃癌前病变(不典型增生及肠化)及胃癌中的表达。
To investigate the expression of p16 in pituitary adenoma.
目的探讨垂体腺瘤中P16蛋白的表达状况。
Methods The expression of P16 protein in 57 cases of rectum cancer, 46 cases of adjacent tissue and 20 cases of normal rectum tissue was tested by immunohistochemical SP method.
方法用SP法进行石蜡切片免疫组化染色，检测57例直肠癌组织、46例癌旁组织及20例正常直肠组织中P 16蛋白的表达。
The expression location of P16 protein could be a characteristic for identifying benign and malignant tissue.
P16蛋白的表达部位对良性及恶性病变可能具有鉴别意义；
Objective: To investigate the correlation of P16 protein expression in breast carcinoma with clinical stage.
目的：研究p 16蛋白在乳腺癌的表达及与临床分期的相关性。
Methods Immunohistochemical staining was used to determine the expression of P16 and P53 in 36 cases of retinoblastoma.
方法对36例视网膜母细胞瘤标本采用免疫组织化学方法观察P 16和P 53表达水平。
The expression of p16 and DAPK protein were detected to analyse the relationship between the promoter hypermethylation and the loss of protein expression.
同时通过检测胃癌组织中基因的蛋白表达水平，了解基因高甲基化与其蛋白表达缺失之间的关系。
Results: Compared with the blank control group, the gastric mucosal APC and P16 protein expression of the model control group was significantly lowered(P<0.05).
结果：与空白对照组相比，模型组大鼠胃黏膜APC和P16蛋白的表达明显降低（P<0.05）。
Conclusion Antisense telomerase RNA can block telomerase activity in SMMC7721 cells accompanied simultaneously with an increased P16 and P21 expression levels.
结论转染反义端粒酶RNA在封闭细胞端粒酶活性表达的同时，伴发P21与P16表达水平的升高。
Objective: To investigate the relationship between expression of CD44V6 and P16 gene and biological behaviors in breast cancer.
目的：探讨CD 4 4 V 6和P16基因蛋白表达与乳腺癌生物学行为的关系。
Conclusions: The over-expression of P16 gene may be involved in ovarian epithelial cancer.
结论：P16蛋白高表达与卵巢癌进展相关。
Conclusions: The over-expression of P16 gene may be involved in ovarian epithelial cancer.
结论：P16蛋白高表达与卵巢癌进展相关。
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