Most of the proteins examined so far proceed oxidative refolding via multiple pathways rather than a single and specific pathway. This is consistent with the folding energy landscape theory.
在已研究过的蛋白质中,大多数蛋白质都是沿着多途径而非单一、特定的途径进行氧化重折叠,这与折叠能量景观学说是一致的。
A schematic flow chart of major oxidative folding and reductive unfolding pathway of AILP was proposed.
本文绘出了AILP的主要氧化折叠和还原解折叠途径草图。
The up-regulation and redistribution of TorsinA is not caused by the pathway of the PMA activating PKC after cells insulted by oxidative stress.
结论扭转蛋白A可能是膜相关蛋白,细胞氧化应激中扭转蛋白A表达上调和重分布变化不是由佛波酯诱导的蛋白激酶C活化途径来实现的。
It is also telling us there are a lot of changes in the nerve - oxidative stress, polyol pathway hyperactivity.
这也告诉我们神经存在多种改变——氧化应激,多元醇通路活性增强。
The mechanism of lovastatin was related to enhance NO pathway and inhibit oxidative stress.
其作用机制可能与洛伐他汀增强NO通路和抗氧化作用有关。
CONCLUSION: Acetaldehyde causes oxidative damage in cardiomyocytes through enhancing cellular ROS level, and induces cardiocytes apoptosis by activating ROS mediated JNK pathway.
结论:乙醛通过增高胞内ros水平损伤心肌细胞,激活ros介导JNK途径诱导细胞凋亡。
CONCLUSION: Acetaldehyde causes oxidative damage in cardiomyocytes through enhancing cellular ROS level, and induces cardiocytes apoptosis by activating ROS mediated JNK pathway.
结论:乙醛通过增高胞内ros水平损伤心肌细胞,激活ros介导JNK途径诱导细胞凋亡。
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