Objective to study the effect and mechanism of amylin upon oral sulfonylurea drugs and its action to stimulate the islet cell secretion of insulin in rats.
目的研究胰淀素对磺脲类降糖药刺激大鼠胰岛细胞分泌胰岛素作用的影响和机制。
Serum insulin concentration at 30 minutes after a 75-g dose of oral glucose was determined at baseline as a measure of insulin secretion.
口服75g葡萄糖30min后血清胰岛素浓度被测定作为胰岛素分泌测定的基线。
Methods: Using in vitro cell culture and animal model to observe the effects of SPA given by oral administration on tumor proliferation, immune function and the ability of IL1, IL2 secretion.
方法：采用体外细胞培养以及小鼠动物模型，观察spa对培养肿瘤细胞的抑制，及其对小鼠动物模型肿瘤增殖、免疫及白介素1和2产生的影响。
Methods: Using in vitro cell culture and animal model to observe the effects of SPA given by oral administration on tumor proliferation, immune function and the ability of IL1, IL2 secretion.
方法：采用体外细胞培养以及小鼠动物模型，观察spa对培养肿瘤细胞的抑制，及其对小鼠动物模型肿瘤增殖、免疫及白介素1和2产生的影响。
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