• The good life turned off tumour-promoting genes (known as oncogenes) -including several that are the target of efforts to develop anti-cancer drugs.

    良好的生活习惯可以抑制引发肿瘤的基因(即:致癌基因)发挥作用,其中的一些致癌基因还是目前正在开发的抗癌药物的研究对象。

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  • The researchers made great progress in the early 1970s, when they discovered that oncogenes, which are cancer-causing genes, are inactive in normal cells.

    研究人员在70年代早期取得了很大进展,他们发现导致癌症的癌基因在正常细胞里是不活跃的。

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  • Transformation of cells is closely related to the inactivation of tumor-resistant genes and the activation of oncogenes.

    癌基因的激活以及抑癌基因的失活被认为与细胞的恶性转化密切相关。

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  • The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.

    癌基因和抑癌基因的发现,细胞信号传导通路的阐明,极大地丰富了人们对细胞癌变机制的认识。

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  • An authentic approach is to build a genomic and proteomic profile of a patient, identify the target oncogenes and prescribe the combination of targeted drugs tailored for that patient.

    一种可信的办法是建立个体化的基因和蛋白图谱,找出目标癌基因并开出专门针对单个病人的靶向治疗药物的组合。

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  • And the occurrence of tumor is closely related to oncogenes and anti-oncogenes.

    而肿瘤的发生与抑癌基因和癌基因密切相关。

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  • A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES;

    癌基因符号前的前缀“v-”表明获得性及由反转录病毒传递的癌基因。

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  • Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.

    病毒癌基因最常为逆转录病毒致癌基因的产物。通常具有转化和蛋白激酶活性。

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  • A small number of new cancer drugs target oncogenes directly, but this may not be the only promising new direction for treating cancers.

    有少数的新抗癌药物是通过直接作用于肿瘤基因发挥作用的,但是这并非治疗癌症唯一有希望的方向。

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  • Conclusion These 2 specifically expressed cDNA fragments isolated by DD-PCR might be the colorectal carcinoma-related oncogenes in quest.

    结论这2条差异显示新基因片段很可能是与大肠癌相关的致癌基因。

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  • Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.

    综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。

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  • Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.

    鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标,因而一直是肺癌研究领域内的热点。

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  • It is known that many related products of oncogenes and anti - oncogenes take part in the signal transduction of grow, proliferation and differentiation of cells.

    近年来的研究发现,许多癌基因和抑癌基因相关产物为细胞生长、增殖、分化等信号转导途径的成员。

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  • Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.

    虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。

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  • Oxidative stress can cause DNA damage, such as DNA strand breaks, point mutations, aberrant DNA cross-linking, and mutations in proto-oncogenes and tumor suppressor genes;

    氧化应激可以导致DNA链断裂、DNA位点突变、DNA双链畸变和原癌基因与肿瘤抑制基因突变等形式的DNA损伤;

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  • Although there is emerging evidence that some microRNAs can function as oncogenes or tumour suppressors, the role of microRNAs in mediating cancer metastasis remains unexplored.

    虽然有事实证明一些微小rna能够起癌基因或者抑癌基因,但是其在肿瘤的侵袭和转移中的作用尚未有研究。

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  • Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.

    因此,探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。

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  • The recent studies demonstrate that cytogenetic alterations, oncogenes, tumor suppressor genes, adhesion molecules and extracellular matrix proteins may play important roles in the process.

    研究发现,细胞遗传学改变、癌基因、抑癌基因、黏附分子及细胞外基质蛋白在涎腺多形性腺瘤的恶变过程中均有一定的作用。

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  • The effects of AFP could be blocked by anti AFP monoclonal antibody. The results indicated that AFP could regulate the growth of HeLa cells through enhancing the expression of these oncogenes.

    AFP的作用均可被抗AFP单克隆抗体所拮抗 。实验结果提示 ,AFP对细胞生长的调节作用可能通过促进这些原癌基因的表达来实现 。

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  • This paper reviews epidemiology studies of associations between polymorphisms in genes involved in immunity regulation, chemical and folate metabolism, DNA repair, cell cycle and oncogenes and NHL.

    虽然有一些研究发现基因多态性可以增加NHL发病的危险性,但还需要更多的流行病学研究。

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  • Oncogenes are genes that can cause healthy cells to transform into tumor cells.

    致癌基因是一种可将健康细胞变成癌细胞的基因。

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  • Oncogenes are sometimes produced as a result of a mutation in one or more of these genes.

    癌基因有时产生于这些基因中的一个或多个突变。

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  • Oncogenes are sometimes produced as a result of a mutation in one or more of these genes.

    癌基因有时产生于这些基因中的一个或多个突变。

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