The influence of the fixed effects on relative clearance of VPA was investigated using Nonlinear Mixed Effect Model(NONMEM) .
用非线性混合效应模型（NONMEM）考察固定效应对丙戊酸相对清除率的影响。
The simplex optimization method about nonlinear programming problem has been used in the mixed acid linear titration and the effect of various factors on computative speed has been discussed.
将非线性规划问题的单纯形加速法用于混合酸的线性滴定计算，同时优化酸浓度及有关条件常数，求出酸浓度的最优解。 讨论了影响单纯形法计算速度的因素。
The simplex optimization method about nonlinear programming problem has been used in the mixed acid linear titration and the effect of various factors on computative speed has been discussed.
将非线性规划问题的单纯形加速法用于混合酸的线性滴定计算，同时优化酸浓度及有关条件常数，求出酸浓度的最优解。 讨论了影响单纯形法计算速度的因素。
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