Methods The expression of MTHFR is detected by RT-PCR in the MTX-Resistant mouse cell lines.
方法采用RT-PCR的方法，对小鼠氨甲蝶呤（MTX）抗性细胞系中MTHFR的表达进行分析。
Variants of MTHFR, for example, have been linked to increased risk of cardiovascular disease.
例如，MTHFR的变异体被认为能增加心血管病的风险。
Methods: PCR-RFLP technique was used for detecting the A677V polymorphism site of MTHFR gene.
方法：运用多聚酶链反应-限制性内切酶片段长度多态性技术(PCR -RFLP)检测MTHFR的677位点多态性。
The residing probability of MTHFR in the cytoplasmic and nuclear was 60.9% and 30.4%, respectively.
亚细胞定位显示，该蛋白存在于细胞质和细胞核的概率分别为60.9%和30.4%。
The phylogenetic tree analysis indicated the broiler MTHFR was closely related to mallard and swan goose.
进化树分析表明，鸡MTHFR氨基酸序列与绿头鸭和鸿雁的关系较近。
This study was to evaluate the effect of MTHFR C677T polymorphism on chemosensitivity and toxicity to 5 FU in patients with gastric carcinoma.
本研究旨在观察mthfr基因C677T多态性对预测胃癌患者对5 -FU的敏感性和化疗毒性的影响。
These results will provide the data for further research of MTHFR gene structure and function, and dietary folic acid supplementation in poultry production.
研究结果可为进一步研究MTHFR基因的结构和功能以及叶酸在家禽生产中的应用提供资料。
Conclusions the C677T mutant frequency of MTHFR might be correlated only with cerebral infarction but not with the frequency of onset of cerebral infarction.
结论MTHFR基因C677T突变可能与脑梗死的发病有关，但与脑梗死发病的次数无关。
Objective To explore relationship between methylenetetra hydrofolate reductase (MTHFR) polymorphism and neural tube defects (NTDs)of women in the northern countryside.
目的探讨北方乡村妇女亚甲基四氢叶酸还原酶（MTHFR）基因多态性与神经管畸形的关系。
Conclusion These findings demonstrated that the genetic variation of MTHFR C677T should be a genetic susceptibility factor for colorectal cancer in a Chinese population.
结论亚甲基四氢叶酸还原酶基因C677T基因多态性可能是我国大肠癌的遗传易感因素。
Results : Detection of MTHFR gene C677T polymorphism was quickly finished by realtime fluorescence quantitative RT - PCR, and the results were proved to be effective by PCR - RFLP.
结果：荧光定量方法可以快速完成MTHFR C677T基因多态性的检测，检测结果得到传统PCR-RFLP方法的证实。
Objective to establish a simple and practical method for detecting the MTHFR gene C677T mutation so as to investigate MTHFR genotypes in the healthy elder and Vascular Dementia (VD).
目的建立一种简便、实用的检测亚甲基四氢叶酸还原酶(MTHFR)等位基因C677 T点突变的方法，并初步观察部分健康老人和老年血管性痴呆(VD)患者中mthfr等位基因C677 T点突变情况。
Conclusion: MTHFR A1298C polymorphism may be associated with reduced risk of rectal cancer, and MTHFR C677T polymorphism with enough folic acid intake may be a protective factor of colon cancer.
结论：MTHFR A 1298 C位点多态性是直肠癌的保护因素，在叶酸摄入充足的条件下，MTHFRC677T多态是结肠癌的保护因素。
The aim of this study is to investigate the relationship between genetic polymorphisms of MTHFR C677T or A1298C and the response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC).
本研究旨在观察mthfr基因C677T、A 1298c多态与非小细胞肺癌(NSCLC)患者对铂类药物为基础的化疗方案敏感性的关系。
The aim of this study is to investigate the relationship between genetic polymorphisms of MTHFR C677T or A1298C and the response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC).
本研究旨在观察mthfr基因C677T、A 1298c多态与非小细胞肺癌(NSCLC)患者对铂类药物为基础的化疗方案敏感性的关系。
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