• CCK activates MAPK in pancreatic acinar cells.

    胰腺腺泡细胞CCK可激活MAPK

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  • Many transcription factors are important MAPK targets, and zinc finger protein is one of them.

    已知有许多转录因子非常重要MAPK靶基因,蛋白就是中间的一类。

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  • ObjectiveTo explore the effect of heat shock response(HSR) on the LPS-stimulated MAPK pathways.

    探讨休克反应HSR内毒素(LPS)所致MAPK信号通路影响

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  • MAPK signaling transduction is a key pathway of cellular proliferation and apoptosis regulation.

    MAPK信号转导通路关键调节细胞增生凋亡通路

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  • The results suggest that hole might be involved in heart development through MAPK signaling pathway.

    研究表明,该基因可能通过参与MAPK信号途径而在心脏发育的过程中起作用。

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  • Conclusion the proliferation of HFL1 induced by FN was through the MAPK signal transduction pathway.

    结论FN诱导HFL1细胞增殖可以通过MAPK信号转导途径实现。

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  • Monoclonal antibody is produced by immunizing animals with synthetic phospho-MAPK/CDK substrate peptides.

    该单克隆抗体合成磷酸化MAPK/CDK底物多肽免疫动物制备。

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  • MAPK cascade pathway can converge extracellular signals and play an important role in signal transduction.

    MAPK级联途径具有信号汇总功能,信号转导过程中起重要作用

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  • Different expression of MAPK and ACS1 to GABA signals may be involved different signal transduction pathway.

    MAPKACS1基因GABA信号不同表达模式可能与不同的信号途径有关。

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  • Objective: to study the mechanisms of oridonin-induced U937 cell apoptosis, and to examine the role of ERK MAPK.

    目的研究冬凌草甲素诱导人组织淋巴瘤u 937细胞凋亡机制ERK激酶凋亡过程中的作用

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  • CONCLUSION: MAPK signal transduction pathway participates the proliferation inhibition of cantharidin on A549 cell.

    结论MAPK信号传导途径参与斑蝥素人肺癌a5 49细胞增殖抑制作用

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  • For MAPK inhibitor assay plated cells were pretreated with inhibitors for at least 30 minutes before drug was added.

    进行MAPK抑制剂分析时,细胞抑制剂处理至少30分钟

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  • These results indicate that MAPK signaling functions, at least in part, as the inducer of ameloblast differentiation.

    这些结果说明MAPK信号至少部分诱导了成釉细胞分化

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  • The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.

    细胞外信号调节激酶丝裂原激活蛋白激酶家族重要成员

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  • CONCLUSION: rat U-II was a potent vasoconstrictor of rat main pulmonary arteries and this response was mediated through MAPK.

    结论:大尾加压素II大鼠主动脉有效血管收缩剂,细胞信号转导通路MAPK的激活参与其收缩效应。

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  • Objective To investigate the expression changes of mitogen activated protein kinase (MAPK) in Alzheimers disease (AD) rat model.

    目的研究人脑胶质瘤组织中丝裂原激活蛋白激酶MAPK表达及活化情况。

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  • In hyperosmotic stress, the HOG-MAPK pathway regulates the signal transduction and expression of numerous genes for cell survival.

    途径高渗应激环境下控制信号转导基因表达,是细胞生存所必需

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  • Objective to investigate the relationship between P38 MAPK activity and apoptosis in drug-resistant cell line of ovarian carcinoma.

    目的研究卵巢癌细胞过程P 38MAPK活性凋亡关系,探讨P 38 MAPK信号转导途径在卵巢癌细胞耐药中的作用。

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  • Phosphorylation of IRS-1 at Ser612 by MAPK downregulates insulin signaling and may be part of a response to high glucose/glucosamine levels (11).

    1612位丝氨酸MAPK磷酸化后会下调胰岛素信号这可能葡萄糖/葡萄糖胺比值的一种反应

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  • Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.

    目的探讨丝裂活化蛋白激酶(MAPK)性高血压致心肌肥大中的作用。

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  • Objective To observe the changes in mitogen-activated protein kinase (MAPK)activity and gene expression after coronary artery balloon injury in rabbits.

    目的探讨丝裂活化蛋白激酶MAPK)在动脉球囊损伤内膜增殖过程中表达变化

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  • Aim: to explore the expression and abnormal activation of mitogen-activated protein kinase (MAPK) in the development and progression of cerebral gliomas.

    目的研究人脑胶质瘤组织丝裂原激活蛋白激酶(MAPK)表达活化情况。

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  • To examine the roles of MAPK signals, we compared the effects of anisomycin and sodium salicylate on the expression of tooth-related differentiation markers.

    为了研究MAPK信号作用我们比较茴香霉素水杨酸作用下牙齿相关的分化标志表达

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  • Using special inhibitor and stimulator of MAPK can make help to understand the complex route system and develop a new route to treat cerebral ischemic disease.

    应用MAPK特异性抑制剂激动有助于进一步认识这一复杂的网络信号传导系统临床防治缺血缺氧性疾病提供有效手段和理论依据。

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  • Conclusions the cytotoxic effects of parvovirus H-1 might affect the gene expression involved in MAPK signal transduction pathway in gastric carcinoma HGC27 cells.

    结论细小病毒H 1细胞毒作用可能与其影响胃癌细胞MAPK信号传导途径中相关基因表达有关

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  • The mitogen-activated protein kinase (MAPK) cascade plays an important role in signal conversion and amplification of extracellular stimuli in eukaryotic organisms.

    促分裂活化蛋白激酶MAPK级联途径信号通路真核生物细胞信号转换放大过程中起重要作用

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  • To investigate the change of mitogen activated protein kinase(MAPK) signaling pathway during prostate cancer progression, and therefore to explore its role on cell proliferation.

    目的:研究前列腺进展中细胞丝活化蛋白激酶MAPK信号通路变化探讨阻断此通路前列腺癌细胞增殖的影响。

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  • The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.

    磷酸化活化的丝裂原活化蛋白激酶,可参与多种细胞生命活动调节基因转录诱导细胞凋亡、调节细胞周期等。

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  • Conclusion: The MAPK transpass activity is promoted during the prostate cancer progression, suggesting that blocking the MAPK transpass can be used as a method for prostate cancer therapy.

    结论MAPK通路的持续活化前列腺恶性进展中起重要作用,阻断此通路可以抑制前列腺癌细胞的增殖。

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  • Objective To study the effects of high glucose on activity of mitogen activated protein kinase (MAPK) in cultured human mesangial cells and to explain the mechanism of diabetic nephropathy.

    目的研究人肾小球系膜细胞丝裂原蛋白激酶MAPK活性影响探讨糖尿病肾病发病中的作用。

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