When she was 19 years old, she made much headway in modeling but still had not made it big.
当沃佳诺娃19岁的时候，她在模特事业上进展顺利但是始终没有飞黄腾达。
Mr Piramal’s great-grandfather was a trader who made it big in textiles in Bombay, as Mumbai was once known.
皮拉马尔的曾祖父在旧时期的孟买是纺织业的大亨。
Gray started growing flowers on a small piece of land. Now he has really made it big and owns flower shops all over England.
格雷在一小块地下开始种花，如今他的生意确实十分红火，英格兰各地都有他的花店。
You fail to take advantage of opportunities: There has probably been more than one occasion where you heard about someone who has made it big and thought to yourself, "I could have thought of that."
你不能抓住机会 ：很多时候，你听说某个人想了个点子还用它干了件大事，这时候你会想：“这个我也想过嘛！”
In the era of "geek chic", scratchy-voice actors are today's big thing and if Nerds had never been made, it could very likely happen today.
在这个“极客时尚”的年代，嗓音沙哑的演员就是当今宠儿，如果《菜鸟大反攻》从未拍过，那它很有可能发生在今天。
Poverty is a big problem in the world, but China has done a good job to deal with it and made the proud achievement.
贫困是世界上的一个大问题，但中国在处理这个问题上做得很好，取得了令人骄傲的成就。
"Ms. Mo made forty or fifty yuan a month back then, so a 0.05-yuan ticket may not be a big deal for her. But for me, it moved me deeply," said 63-year-old Shao.
“那时候莫老师一个月能挣四五十元，所以0.05元的票对她来说可能没什么大不了的。但对我来说，它深深地打动了我，”63岁的邵说。
So, if portability to new architectures is trivial, why is such a big deal made of it?
因此，如果到新体系架构的可移植性是如此平凡，那么为什么它会如此重要呢？
This made sense when all future development was meant to use .NET, but when that plan changed and native code regained its position as the preferred development environment, it was a big problem.
计划之初，所有的开发都打算用.NET进行，但是渐渐计划成变化，原生代码还是成了首选的开发环境。这的确是个很大的问题。
When the data were put online Dr Szalay thought it was only a matter of time before someone made a big discovery.
当数据上线时，Szalay认为这不过是做出一些重大发现之前的小事件。
USPS says it will lose nearly $8 billion this fiscal year and as much as $238 billion by 2020 unless big changes are made.
美国邮政总局认为，除非在做出重大的改变，否则在今年的财政收入将会损失接近80亿，并且在到2020年几乎会是2380亿。
It took a while, but Google has made its big move as a local shopping inventory gatekeeper.
做一个本地购物的门户这个举措，Google还是话了一些时间。
It's made us, it's formed us. It's such a big part of my life so it will be really sad. '.
这是我生命中如此巨大的组成部分，它的完结将是让我感觉难舍和痛心的。
Rain, strong winds and the rough water in the Channel made it easy to imagine what the sea might look like in a big storm.
海峡上方下着雨，刮着强风，水面波涛汹涌，看到这样的场景，不难想象大风暴来时大海会是什么样。
We had a big problem in one of our early stages, especially because the economy was mainly made by me (a programmer), and it wasn't properly planned.
我们早期的进展存在很大的问题，尤其是因为经济系统主要是由我(一个程序员)设计的，它没有被恰当的计划。
Maybe I made a big mistake by likening it to an organic chemistry course--I don't mean to turn you off.
也许我把金融市场学跟有机化学进行类比是个很大的错误- 我并没打算让你们感到厌烦。
If they were emailing with someone that was requesting strange things that made them uncomfortable, would they tell you because they know you would "over-react" and make a big deal out of it?
如果他们和某个人互发邮件，这个人要求孩子们做他们觉得不舒服的事情，孩子们会不会因为他们知道你将会“反应过度强烈”，并且胡乱猜测地大喊大叫而告诉你这件事呢？
"For me, it was a big, 'phew,' — I had finally made a choice and a big burden was off my shoulders," said Lina, who works for a medical diagnostics company.
“对于我来说，这是极大的解脱，我最终做了选择，甩开了肩上沉重的负担，”莉娜说，她现在在一家医学诊断公司工作。
But the big problem with consumer spending is that if you buy a product made outside the U. S., it doesn't encourage domestic investment. And that's what we really need.
但是消费开销的大问题是，如果你买一个在美国外生产的产品，并不能支持我们真正想要的国内的资本。
It said the EU's big bail-out fund would be temporary, but it is being made permanent.
它称欧盟巨额的纾困基金只是权宜之计，但是现在正成为一个永久的机制。
A big European bail-out fund was supposed to be a temporary measure; now it is being made permanent.
欧洲经济援助基金本应该是一个临时举措，为现在它正在趋于永久。
It was quite a big black one, and made me jump. He went the other way and slithered pretty quickly up an embankment.
这是一条不小的蛇，吓得我跳了起来，幸好它朝另外一个方向快速爬上了一处堤岸。
As for the first, "the Girl with the Dragon Tattoo," she told me that it was thoroughly edited, and that big changes were made, before he died.
至于第一本《龙纹身的女孩》，葛丁告诉我，它在作家去世之前就被彻底的编辑过一遍，改动很多。
In the long run, it really shouldn't have been that big a surprise to me that I feel best eating the simple foods that nature provides instead of man-made concoctions.
长期下来，吃简单自然的食物比吃人工合成的食物让我感觉更好，这一点不会再是个令我吃惊的问题。
Big Ben also had two really bad attacks of colic and unlike most horses, Ben made it through.
大本曾经有两次很严重的急腹痛，不像大多数的马那样，他挺过来了。
The big emerging economies—Brazil, China, India and South Africa—made it clear in turn that a second commitment was their top priority.
但那些新兴国家们---巴西，中国，印度，南非---随后回应表明第二个承诺期是他们的重中之重。
The big emerging economies—Brazil, China, India and South Africa—made it clear in turn that a second commitment was their top priority.
但那些新兴国家们---巴西，中国，印度，南非---随后回应表明第二个承诺期是他们的重中之重。
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