Conclusion As an inhibitor of JAK, AG490 can influence the function of normal cells.
结论AG490作为一种酪氨酸激酶抑制剂，能影响正常细胞的功能。
JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.
JAK2是一种组成性酪氨酸激酶，能激活JAK - STAT信号传导途径。
Another form of action game are the platform games like Jak and Daxter, Crash Bandicoot and Rayman 2.
另一种动作游戏是平台游戏，例如杰克与达斯夫，古惑狼：邪恶意志和雷曼2。
After being met at the airport by a driver and shuttled to my new accommodations, a member of the JAK production team met up with me.
有司机来机场接我，把我送到我的新住处后，JAK制作组的一个成员来和我见了面。
The present invention relates to compounds of formula (I) useful as inhibitors of protein kinases, particularly of JAK family kinases.
本发明涉及可用作蛋白激酶、特别是JAK家族激酶的抑制剂的式(i)化合物。
The JAK/STAT pathway that contributes to signal transduction by cytokines, growth factors and hormones is universally activated in leukemias.
JAK/S TAT通路是细胞因子、生长因子、激素等广泛应用的信号转导通路，白血病形成中普遍存在JAK/STAT通路的持续激活。
STAT proteins are activated by G-protein coupled receptors, while it has not been reported whether CCK receptors, a kind of G-protein coupled receptors, can activate JAK/STAT pathway.
STAT蛋白可被G 蛋白偶联受体激活，而CCK 受体作为一种G 蛋白偶联受体，是否对JAK／STAT通路具有直接激活作用，尚未见报道。
We incidentally found that STAT1C overexpression cause aberrant STAT activation in LL2 cells. Further studies on the underlying mechanisms may explore a novel regulatory system of JAK/STAT pathway.
我们偶然发现送入细胞内的STAT1C过量表现会造成LL2细胞异常的STAT蛋白活化，进一步研究其机制也许能发现一些新的JAK/STAT讯息传递路径的调节系统。
We incidentally found that STAT1C overexpression cause aberrant STAT activation in LL2 cells. Further studies on the underlying mechanisms may explore a novel regulatory system of JAK/STAT pathway.
我们偶然发现送入细胞内的STAT1C过量表现会造成LL2细胞异常的STAT蛋白活化，进一步研究其机制也许能发现一些新的JAK/STAT讯息传递路径的调节系统。
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