Both its therapeutic and side effects is believed to result from its interaction with DNA.
它的疗效和副作用被认为是由于它与DNA之间存在有相互作用。
The interaction with DNA and bovine serum albumin (BSA) were studied by fluorescence spectra and agarose gel electrophoresis.
运用荧光光谱法、琼脂糖凝胶电泳法分别研究了配合物与DNA和BSA的作用。
Interaction of DNA with small molecules, especially drug molecules affected physiological and physical chemical character of DNA and changed the transfer and copy of DNA.
小分子物质，特别是一些药物分子，与DNA的作用，影响到DNA的生理和物理化学性质，改变了DNA的转译和复制。
These results will be useful for further understanding the interaction of DNA with adriamycin.
这些结果为深入理解阿霉素与DNA的相互作用提供了帮助。
The results above will provide theoretical basis for understanding the interaction of denatured DNA with drugs and the repair of denatured DNA.
上述结果将为理解变性DNA与药物分子的相互作用以及变性DNA的修复提供理论依据。
Core processes of epigenetic inheritance include DNA methylation, histone modification, nucleosome remodeling, nuclear dynamics and chromatin interaction with non-coding RNAs.
核心过程的表观遗传的产业包括DNA甲基化、组蛋白改性、核小体重建、核染色质动力学和互动子都存在。
The interaction of metal complex of norfloxacin (NFLX) with herring sperm DNA and its characteristic were studied by UV and visible spectrophotometry.
用紫外可见分光光度法研究了诺氟沙星(NFLX)的光谱特性及其金属络合物与鲱鱼精dna的相互作用。
Telomeric binding proteins protect telomeric DNA while telomeric associated proteins have effect on telomere through interaction with telomeric binding proteins.
端粒结合蛋白直接保护端粒DNA，端粒相关蛋白通过与端粒结合蛋白的相互作用间接影响端粒的功能。
In this paper, the Electrochemistry behavior of the anticancer drugs 8-azaguanine (8-ag) and 6-mercaptopurine (6-mp) have been studied and the interaction of 8-ag with DNA has been studied too.
本论文用电化学的方法研究了两种抗癌药物——8 -氮鸟嘌呤和6 -巯基嘌呤的电化学性质，同时就其与DNA的相互作用也做了初步的探讨。
Normal heredity function of DNA depends on the physical and chemical interaction of other molecules with DNA.
DNA在生物遗传中具有特殊功能，能否行使正常的遗传功能依赖与其他分子的物理，化学相互作用。
The interaction of hematoporphyrin dihydrochloride (HD) with DNA was studied by using neutral red (NR) as a probe.
以中性红(nr)作探针研究了血卟啉(HD)与DNA的相互作用。
The spectrophotometric studies show that the modes of these two complexes interacting with DNA were electrostatic interaction.
结果表明，两种配合物均是通过静电作用与DNA结合的。
In addition, we also studied interaction mechanism between these ligands and their rare earth complexes with DNA.
又探讨了这些配体和稀土金属配合物与DNA的相互作用。
The interaction between curcumin and DNA were investigated by means of cyclic voltammetry and differential pulse voltammetry with DNA-modified glassy carbon electrodes.
采用循环伏安法和差示脉冲伏安法，研究了姜黄素在DNA修饰玻碳电极上与DNA的相互作用。
DNA replication, repairing and recombination must depend on the interaction with the protein.
DNA的复制、修复与重组，必须依赖与蛋白质的相互作用。
The interaction of the 1,4-dihydropyridine derivative(1,4-DHP) with calf thymus DNA(CT-DNA) was studied by using fluorensence spectroscopy.
用荧光光谱研究了1，4-二氢吡啶衍生物（1，4-DHP）与小牛胸腺DNA（CT-DNA）的相互作用。
The salt effect showed that the interaction of the RF with DNA was mainly electrostatic interaction.
盐效应表明，RF与DNA之间的作用方式主要是静电作用。
The hybridization event was recognized by the different FRET efficiencies due to different interaction abilities of single-stranded and double-stranded DNA with the polymer.
由于单股和双股DNA与聚合体之间具有不同的相互作用能力，因而可通过不同荧光能量共振转移效率识别杂交事件。
Investigating the interaction mechanism of metal or metal complex with biomolecule, such as DNA, protein and amino acid, provides a starting point for the diagnosis of metal-induced human disease.
金属及其配合物与dna、蛋白质、氨基酸等生物分子的作用机理研究，是诊断和治疗由金属引起的疾病的重要环节。
A research on the interaction between DNA and vitamin-B6 was conducted with an electrode modified by DNA.
利用探针分子通过电化学循环伏安法研究了鱼精脱氧核糖核酸与维生素b6的相互作用。
METHODS: Review interaction styles of DNA with DNA targeting molecules and bioassay guided isolation of active principles from natural medicinal plants.
方法：综述DNA与其靶向分子的作用方式以及DNA为作用靶的生物活性筛选系统跟踪分离天然植物药活性成分的情况。
Aim To investigate the electrochemical behaviors of Mitomycin C and its interaction with calf thymus DNA. Methods The cyclic voltammetry was carried out at a paraffined graphite electrode.
应用循环伏安法研究了药物丝裂霉素与小牛胸腺DNA在自制的浸蜡石墨电极上的相互作用。
Deacetylation of p53 occurs through interaction with the SIRT1 protein, a deacetylase that may be involved in cellular aging and the DNA damage response (19).
SIRT1蛋白，一种涉及到细胞衰老和DNA损伤反应的去乙酰基酶能够与p53结合，促使后者的去乙酰化（19）。
Deacetylation of p53 occurs through interaction with the SIRT1 protein, a deacetylase that may be involved in cellular aging and the DNA damage response (19).
SIRT1蛋白，一种涉及到细胞衰老和DNA损伤反应的去乙酰基酶能够与p53结合，促使后者的去乙酰化（19）。
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