Levels of messenger RNA and expression of HMGA1 and INSR proteins were also determined in patients with type 2 DM and control patients.
在2型糖尿病和对照患者也进行了信使RNA的水平和HMGA1与INSR的蛋白表达测定。
Objective: to probe the role of androgen receptor (ar) and insulin receptor (INSR) in pathogenesis of asymmetric polycystic ovaries (PCO) as local factors.
目的:探讨雄激素受体(AR)和胰岛素受体(INSR)在不对称性多囊卵巢(PCO)局部发病机制中的作用。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
方法:对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测,并对突变的外显子进行核苷酸序列分析。
The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.
这个变异称为IVS5-13insC,造成HMGA1蛋白的功能损伤,HMGA1蛋白是调节胰岛素受体基因(INSR)表达的辅助因子。
Objective To investigate insulin receptor (INSR) genotype exon 17 frequencies in women with polycystic ovary syndrome(PCOS) and to elucidate its role in the pathogenesis of PCOS.
目的探讨胰岛素受体基因外显子17与多囊卵巢综合征(PCOS)发病的关系。
Objective To investigate insulin receptor (INSR) genotype exon 17 frequencies in women with polycystic ovary syndrome(PCOS) and to elucidate its role in the pathogenesis of PCOS.
目的探讨胰岛素受体基因外显子17与多囊卵巢综合征(PCOS)发病的关系。
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