Methods tropisetron hydrochloride was synthesized from indol-3-yl carboxylic acid by chlorination and condensation with tropic alcohol lithium, then salt formation with hydrochlororic acid.
方法:以吲哚-3-甲酸为起始原料,酰氯化后与托品醇锂发生缩合反应,再与盐酸成盐制得盐酸托烷司琼。
Unsymmetrical bisindolylalkane with 73%~99% of yields were synthesized by iodine catalyzation from indole with(1H-indol-3-yl)(alkyl)methanol under solvent free condition at room temperature.
在室温以及无溶剂条件下,吲哚与烷基-3-吲哚基甲醇在碘的催化下以73%~99%的高收率得到不对称双吲哚烷基化合物。
Unsymmetrical bisindolylalkane with 73%~99% of yields were synthesized by iodine catalyzation from indole with(1H-indol-3-yl)(alkyl)methanol under solvent free condition at room temperature.
在室温以及无溶剂条件下,吲哚与烷基-3-吲哚基甲醇在碘的催化下以73%~99%的高收率得到不对称双吲哚烷基化合物。
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