• The effect of IGFBP-3 on the growth hormone promoter activity stimulated by triiodothyronine was determined by dual-luciferase reporter assay.

    通过双荧光素酶报告基因测定法测定了IGFBP-3对由三碘甲状腺素刺激的生长激素启动子活性的影响。

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  • Low IGFBP-1 levels are typically found in obese and inactive individuals.

    肥胖和缺乏锻炼的人群中igfbp - 1蛋白的浓度通常较低。

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  • The expression of IGFBP-5 in some non-neoplastic diseases also decrease, so it …

    在一些非肿瘤性疾病中IGFBP-5表达也减少,有必要做更深一步的研究。

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  • In this study, we have explored the developmental role of IGFBP-3 using the zebrafish model.

    本研究使用斑马鱼模型探索了IGFBP - 3的在胚胎发育中的功能。

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  • The higher gene expression of IGFBP-6 may be induced the developmental skeleton defect in CCF rat.

    CCF大鼠软骨组织内IGFBP-6的高表达可能与骨骼发育畸形的发生密切相关。

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  • Objective: to study the expression of IGFBP-2 protein in gastric cancer peritoneal metastasis tissues.

    目的:探讨胰岛素样生长因子结合蛋白2 (IGFBP - 2)在胃癌腹膜转移组织中的表达。

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  • Conclusions Serum IGFBP-1 participates in the growth of normal and IUGR rat fetuses as an inhibiting factor.

    结论血清igfbp - 1作为生长抑制因子参与正常胎鼠发育及IUGR的发生。

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  • Modified forms include IGFBP-1 attached to a polymer or two IGFBP-1 molecules attached to opposite ends of a polymer.

    修饰形式包括接合到聚合物的IGFBP - 1和两个接合到聚合物之相对两端上的IGFBP - 1分子。

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  • Objective To explore the role of IGFBP-1 in the normal growth and intrauterine growth retardation (IUGR) in rat fetuses.

    目的探讨胰岛素样生长因子结合蛋白- 1 (IGFBP - 1)在正常胎鼠发育和胎鼠宫内发育迟滞(IUGR)发生中的作用。

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  • Methods The serum IGF-1 level was measured by specific radioimmunoassays(RIA); the serum IGFBP-3 level by immunoradio-assays(IRMA).

    方法采用放射免疫分析法(RIA)测定血清中IGF-1水平,免疫放射分析法(IRMA)测定IGFBP-3水平。

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  • Conclusions There are positive correlations between serum (IGFBP-3) and age, pubertal stage, height and serum IGF-1 level respectively.

    结论血清igfbp - 3水平与年龄、青春发育期、身高及血清igf - 1水平明显相关。

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  • There were significant differences of IGFBP-1 expressions in gestational hypertension , mind preeclampsia and severe preeclampsia groups (P<0.05).

    妊娠期高血压、轻、重度子痫前期组间IGFBP-1表达逐渐增强,差异有显著性(均P<0.05)。

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  • After that, the serum insulin like growth factor 1 (IGF 1), insulin like growth factor binding protein 3 (IGFBP 3), and growth speed were observed.

    观察用药后生长速率、血清胰岛素样生长因子-1 (IGF - 1)、血清胰岛素样生长因子结合蛋白3 (IGFBP - 3)等指标的变化。

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  • Objective to determine the levels of insulin-like growth factor binding protein-2 (IGFBP-2) in glioma tumor tissue and their clinical significance.

    目的探讨不同病理分级胶质瘤中胰岛素样生长因子结合蛋白2 (IGFBP - 2)的表达情况,以及与其他分子及临床预后的相关性。

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  • For the current study, investigators looked at whether blood levels of a protein known as IGFBP-1 were related to the risk of developing the cancer.

    在本项研究中,研究者调查了血液中igfbp - 1蛋白的浓度是否与癌症发病率相关。

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  • Objective: to explore the significance of the choice of insulin-like growth factor binding protein 1 (IGFBP-1) on the induced labor of post-term pregnancy.

    目的:探讨胰岛素样生长因子结合蛋白-1 (IGFBP - 1)对延期妊娠引产时机选择的意义。

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  • Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condit...

    新近研究提示,在基础和应激条件下,生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白(GH IGF IGFBP)轴对调节肌肉蛋白质代谢起着核心作用。

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  • Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condition.

    新近研究提示,在基础和应激条件下,生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白(GH IGF IGFBP)轴对调节肌肉蛋白质代谢起着核心作用。

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  • It's too early, he said, to tell whether measuring IGFBP-1 levels, specifically, could help in detecting the cancer. But future studies should investigate this.

    对于测定IGFBP - 1浓度能否对检测癌症有所帮助来说,现在还太早,今后的研究还应该进一步关注。

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  • Objective to evaluate the relationship between circulating levels of insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and colorectal cancer.

    目的综合评价血清胰岛素样生长因子1 (IGF - 1)、胰岛素样生长因子结合蛋白3 (IGFBP - 3)水平和大肠癌的关系。

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  • Objective to study the relationship between fetal development and cord serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3) levels at birth.

    目的:探讨新生儿脐血中胰岛素样生长因子- I (IGF - I)和胰岛素样生长因子结合蛋白- 3 (IGF BP - 3)水平与胎儿宫内生长发育的关系。

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  • ObjectiveTo explore the detection significance of insulin-like growth factor-I(IGF-I), IGF-binding protein-3(IGFBP-3) in children with acute lymphoblastic leukemia(ALL).

    目的探讨胰岛素样生长因子-Ⅰ(IGF-Ⅰ)及胰岛素样生长因子结合蛋白-3(IGFBP-3)在急性淋巴细胞白血病(ALL)儿童中检测的意义。

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  • Objective: to investigate plasma levels of insulin like growth factor 1 (IGF 1) and its binding protein 3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.

    目的:观察2型糖尿病病人血中胰岛素样生长因子-1 (IGF - 1)及胰岛素样生长因子结合蛋白-3 (IGFBP - 3)水平与糖尿病及微血管病变的关系。

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  • Objective to study the biological activity of the human insulin like growth factor binding protein 1 (IGFBP 1) and insulin like growth factor (IGF 1) on endothelial cell proliferation.

    目的观察胰岛素样生长因子结合蛋白1对人血管内皮细胞的影响及其对胰岛素样生长因子的调节作用。

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  • Objective to investigate the expression of insulin-like growth factor-binding protein-5 (IGFBP-5) in full-term rats with hyperoxia-induced chronic lung diseases (CLD) and its mechanism.

    目的研究胰岛素样生长因子结合蛋白5 (IGFBP - 5)在高体积分数氧致新生大鼠慢性肺疾病(CLD)中的表达及作用机制。

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  • The men and women with the lowest levels of IGFBP-1 were twice as likely as those with higher levels to develop pancreatic cancer, according to the report in the journal cancer Research.

    根据《癌症研究杂志》,IGFBP - 1浓度低的男性和女性患胰腺癌的几率比浓度高的人群高一倍。

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  • To observe the clinical value of insulin-like growth factor (IGF) -1 and IGF binding protein (IGFBP) -3 in diagnosis and therapeutic effect judging of growth hormone deficiency (GHD) in children.

    目的探讨胰岛素样生长因子1 (IGF - 1)及其结合蛋白3 (IGFBP - 3)在儿童生长激素缺乏症(GHD)诊断及疗效判断中的价值。

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  • To observe the clinical value of insulin-like growth factor (IGF) -1 and IGF binding protein (IGFBP) -3 in diagnosis and therapeutic effect judging of growth hormone deficiency (GHD) in children.

    目的探讨胰岛素样生长因子1 (IGF - 1)及其结合蛋白3 (IGFBP - 3)在儿童生长激素缺乏症(GHD)诊断及疗效判断中的价值。

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