The effect of IGFBP-3 on the growth hormone promoter activity stimulated by triiodothyronine was determined by dual-luciferase reporter assay.
通过双荧光素酶报告基因测定法测定了IGFBP-3对由三碘甲状腺素刺激的生长激素启动子活性的影响。
Inhibiting IGFBP-3 allowed the peptide to exert a more potent effect.
抑制性的IGFBP - 3让肽起一个更有力的作用。
Low IGFBP-1 levels are typically found in obese and inactive individuals.
肥胖和缺乏锻炼的人群中igfbp - 1蛋白的浓度通常较低。
The expression of IGFBP-5 in some non-neoplastic diseases also decrease, so it …
在一些非肿瘤性疾病中IGFBP-5表达也减少，有必要做更深一步的研究。
Methods The CAM technique was used on study of the activity on IGFBP-1 and IGF-1.
方法采用CAM技术在体研究IGF 1、IGFBP 1对鸡胚绒毛尿囊膜血管生长的影响。
In this study, we have explored the developmental role of IGFBP-3 using the zebrafish model.
本研究使用斑马鱼模型探索了IGFBP - 3的在胚胎发育中的功能。
The higher gene expression of IGFBP-6 may be induced the developmental skeleton defect in CCF rat.
CCF大鼠软骨组织内IGFBP-6的高表达可能与骨骼发育畸形的发生密切相关。
Objective: to study the expression of IGFBP-2 protein in gastric cancer peritoneal metastasis tissues.
目的：探讨胰岛素样生长因子结合蛋白2 (IGFBP - 2)在胃癌腹膜转移组织中的表达。
Conclusions Serum IGFBP-1 participates in the growth of normal and IUGR rat fetuses as an inhibiting factor.
结论血清igfbp - 1作为生长抑制因子参与正常胎鼠发育及IUGR的发生。
Modified forms include IGFBP-1 attached to a polymer or two IGFBP-1 molecules attached to opposite ends of a polymer.
修饰形式包括接合到聚合物的IGFBP - 1和两个接合到聚合物之相对两端上的IGFBP - 1分子。
Objective To explore the role of IGFBP-1 in the normal growth and intrauterine growth retardation (IUGR) in rat fetuses.
目的探讨胰岛素样生长因子结合蛋白- 1 (IGFBP - 1)在正常胎鼠发育和胎鼠宫内发育迟滞(IUGR)发生中的作用。
Methods The serum IGF-1 level was measured by specific radioimmunoassays(RIA); the serum IGFBP-3 level by immunoradio-assays(IRMA).
方法采用放射免疫分析法（RIA）测定血清中IGF-1水平，免疫放射分析法（IRMA）测定IGFBP-3水平。
Conclusions There are positive correlations between serum (IGFBP-3) and age, pubertal stage, height and serum IGF-1 level respectively.
结论血清igfbp - 3水平与年龄、青春发育期、身高及血清igf - 1水平明显相关。
Murine serum insulin? Like growth factor1 (IGF? 1) and insulin? Like growth factor binding protein3 (IGFBP? 3) were determined by ELISA.
ELISA方法检测裸鼠血清中胰岛素样生长因子(IGF ？1)和胰岛素样生长因子结合蛋3 (IGFBP ？ 3)含量变化。
There were significant differences of IGFBP-1 expressions in gestational hypertension , mind preeclampsia and severe preeclampsia groups (P<0.05).
妊娠期高血压、轻、重度子痫前期组间IGFBP-1表达逐渐增强，差异有显著性（均P<0.05）。
After that, the serum insulin like growth factor 1 (IGF 1), insulin like growth factor binding protein 3 (IGFBP 3), and growth speed were observed.
观察用药后生长速率、血清胰岛素样生长因子-1 (IGF - 1)、血清胰岛素样生长因子结合蛋白3 (IGFBP - 3)等指标的变化。
Objective to determine the levels of insulin-like growth factor binding protein-2 (IGFBP-2) in glioma tumor tissue and their clinical significance.
目的探讨不同病理分级胶质瘤中胰岛素样生长因子结合蛋白2 (IGFBP - 2)的表达情况，以及与其他分子及临床预后的相关性。
For the current study, investigators looked at whether blood levels of a protein known as IGFBP-1 were related to the risk of developing the cancer.
在本项研究中，研究者调查了血液中igfbp - 1蛋白的浓度是否与癌症发病率相关。
This indicated that the lower IGF-1 and IGFBP-3 levels had no relation with fetal growth, may have relation with the growth retardation after birth.
提示IGF-1／IGFBP-3水平降低与胎儿期体格生长无关； 中义摘要可能与患儿生后生长发育迟缓有关；
Objective: to explore the significance of the choice of insulin-like growth factor binding protein 1 (IGFBP-1) on the induced labor of post-term pregnancy.
目的：探讨胰岛素样生长因子结合蛋白-1 (IGFBP - 1)对延期妊娠引产时机选择的意义。
Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condit...
新近研究提示，在基础和应激条件下，生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白(GH IGF IGFBP)轴对调节肌肉蛋白质代谢起着核心作用。
Recent researches indicate that the GH IGF IGFBP axis plays a crucial part in regulating the metabolism of muscle protein on both basal and stress condition.
新近研究提示，在基础和应激条件下，生长激素胰岛素样生长因子胰岛素样生长因子结合蛋白(GH IGF IGFBP)轴对调节肌肉蛋白质代谢起着核心作用。
It's too early, he said, to tell whether measuring IGFBP-1 levels, specifically, could help in detecting the cancer. But future studies should investigate this.
对于测定IGFBP - 1浓度能否对检测癌症有所帮助来说，现在还太早，今后的研究还应该进一步关注。
Objective to evaluate the relationship between circulating levels of insulin-like growth factor-1 (IGF-1), IGF-binding protein-3 (IGFBP-3) and colorectal cancer.
目的综合评价血清胰岛素样生长因子1 (IGF - 1)、胰岛素样生长因子结合蛋白3 (IGFBP - 3)水平和大肠癌的关系。
In earlier studies, the team found that insulin-like growth factor binding protein-3 (IGFBP-3) binds Humanin and tempers its effects on promotion of cell survival.
在早期研究中，团队发现胰岛素样生长因子结合蛋白- 3 (IGFBP - 3)与人体肽相关，并缓和在促进细胞存活的作用。
Objective to study the relationship between fetal development and cord serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3) levels at birth.
目的：探讨新生儿脐血中胰岛素样生长因子- I (IGF - I)和胰岛素样生长因子结合蛋白- 3 (IGF BP - 3)水平与胎儿宫内生长发育的关系。
ObjectiveTo explore the detection significance of insulin-like growth factor-I(IGF-I), IGF-binding protein-3(IGFBP-3) in children with acute lymphoblastic leukemia(ALL).
目的探讨胰岛素样生长因子-Ⅰ（IGF-Ⅰ）及胰岛素样生长因子结合蛋白-3（IGFBP-3）在急性淋巴细胞白血病（ALL）儿童中检测的意义。
Objective: to investigate plasma levels of insulin like growth factor 1 (IGF 1) and its binding protein 3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.
目的：观察2型糖尿病病人血中胰岛素样生长因子-1 (IGF - 1)及胰岛素样生长因子结合蛋白-3 (IGFBP - 3)水平与糖尿病及微血管病变的关系。
Objective to study the biological activity of the human insulin like growth factor binding protein 1 (IGFBP 1) and insulin like growth factor (IGF 1) on endothelial cell proliferation.
目的观察胰岛素样生长因子结合蛋白1对人血管内皮细胞的影响及其对胰岛素样生长因子的调节作用。
Objective to investigate the expression of insulin-like growth factor-binding protein-5 (IGFBP-5) in full-term rats with hyperoxia-induced chronic lung diseases (CLD) and its mechanism.
目的研究胰岛素样生长因子结合蛋白5 (IGFBP - 5)在高体积分数氧致新生大鼠慢性肺疾病(CLD)中的表达及作用机制。
应用推荐