• Conclusions: IGF-2 may contribute to the DM outbreak and the occurrence of osteoporosis.

    结论IGF - 2可能参与2型糖尿病进程骨质疏松发生

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  • Methods: Height, weight, fasting serum C-peptide, IGF-2, and BMD were measure in 96 patients with DM.

    方法:962型糖尿病患者测量身高、体质量骨密度、骨密度以及空腹血清CIGF - 2水平。

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  • There are evidences that IGF-2 increases cell proliferation, inhibits apoptosis and raises local infiltration and transfer in many tumor cells.

    证据证明IGF - 2许多肿瘤细胞中可使细胞增殖增加抑制凋亡增加局部浸润转移

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  • IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth.

    IRS - 2正常营养动态平衡至关重要,因为能同时介导外周胰岛素作用B -细胞中igf - 1作用

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  • In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2).

    脊椎动物中IRS-2脚手架蛋白发挥作用,协调胰岛素/IGF信号级联通路中的不同分支2)。

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  • Objective: to investigate plasma levels of insulin like growth factor 1 (IGF 1) and its binding protein 3 (IGFBP 3) in type 2 diabetes and their relationship with microangiopathy.

    目的观察2糖尿病病人胰岛素生长因子-1 (IGF - 1)胰岛素样生长因子结合蛋白-3 (IGFBP - 3)水平糖尿病及微血管病变的关系

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  • Objective To investigate the relationship between insulin-like growth factor-1(IGF-1)and type 2 diabetic macroangiopathy.

    目的研究2糖尿病大血管病变患者血清胰岛素样生长因子-1IGF-1)水平变化及其临床意义。

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  • Associations with 2-h glucose, insulin, and HOMA-IR remained significant after further adjustment for IGF-1, parathyroid hormone, calcium, physical activity, and social class.

    经过进一步调整IGF - 1甲状旁腺激素体力活动社会地位后,和2 -水合葡萄糖胰岛素HOMA - IR的联系仍然重要

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  • Associations with 2-h glucose, insulin, and HOMA-IR remained significant after further adjustment for IGF-1, parathyroid hormone, calcium, physical activity, and social class.

    经过进一步调整IGF - 1甲状旁腺激素体力活动社会地位后,和2 -水合葡萄糖胰岛素HOMA - IR的联系仍然重要

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