The beads are DNA segments wrapped around the histone.
这些珠子是包裹在组蛋白上的DNA片段。
A small molecule called an acetyl group attaches to a particular histone known as H4.
一个小小的分子称作一个乙酰基团，它黏在一个称作h4的特殊组蛋白上。
In addition to the MHC, this region on chromosome 6 also contains a cluster of histone genes.
除了MHC外，6号染色体上的该区域也包含一组组蛋白基因。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
Therefore, histone lysine demethylases may serve as a new target for anti-cancer therapy.
组蛋白赖氨酸去甲基化酶有可能成为一个新的抗肿瘤治疗靶标。
H1 histone plays an important role in innate immune responses of goldfish.
金鱼h 1组蛋白及其来源肽在金鱼先天免疫防御中发挥作用。
The repressive mark was composed of three methyl groups attached to a lysine on the H4 histone.
抑制性标记由3个甲基基团组成，结合到组蛋白H4的一个赖氨酸残基上。
Chromatin consists of coiled DNA bound to basic proteins called histones and non-histone proteins.
染色质由卷曲的DNA、组蛋白和非组蛋白组成。
Sensitive assay system for inhibitor screening and kinetic assays of HDAC1 (histone deacetylase 1).
一种用于抑制剂筛选和HDAC1动力学检测的敏感检测系统。
Their erythrocytes have histone H_5 with same electrophoretie mobility as that in bird's erythrocytes.
它们的红细胞中都有与鸟类红细胞具有相同迁移率的组蛋白H_5。
The system of Epigenetics includes DNA methylation, RNA-interfering, genome imprinting and histone code and so on.
表遗传体系包括DNA甲基化、RNA干涉、基因组印迹和组蛋白密码等多方面。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
Our data provide new insights into the function of histone methylation and chromatin organization in genome function.
我们的数据提供了一个在基因组功能中组蛋白甲基化和染色质组织的新观点。
Contrast to HMG histone H1 showed obvious inhibition effect on transcriptional activity of all of the rat liver nuclei.
相反，组蛋白h1则可抑制各年龄组鼠肝细胞核的转录活性。
Histone H3 is one of the four histones, along with H2A, H2B, and H4, which form the eukaryotic nucleosome octamer core.
组蛋白H3与其他类型的组蛋白分子H2A，H2B，H4共同构成了真核生物核小体的八聚体核心。
The level of his-tone acetylation is determined by the activities of histone acetyltransferases and histone deacetylases.
组蛋白乙酰转移酶和组蛋白去乙酰酶活性共同决定了组蛋白的乙酰化水平。
They have discovered an enzyme - histone deacetylase 5 (HDAC5) - has a significant influence on the effect of the hormone.
他们发现，大脑中有一个“开关”控制瘦素的作用，它就是一种名为组蛋白去乙酰化酶5（HDAC5）的酶。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达，而去乙酰化则抑制基因表达。
We will discuss methods to address these challenges in the context of analyzing histone modifications and DNA methylation data.
我们将在分析组蛋白修饰和DNA甲基化数据的背景下，讨论解决这些挑战的方法。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
The core consists of 140 base pair of DNA wrapped around a globular histone bead containing two each of histones H2A, H2B, H3 and H4.
核小体核心由140个碱基对的DNA围绕一个组蛋白小球组成，每一个组蛋白小球包含两个H_2A、H_2B、H3和H4的四聚体分子。
When methyl groups are added to a histone, they modify its properties and alter the frequency at which a particular gene is expressed.
当甲基加到组蛋白后，这些基团会修饰它的性质并改变它上面特定基因的表达频率。
As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.
如同阿尔茨海默病鼠，增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。
OBJECTIVE: to investigate the molecular mechanisms of histone deacetylase inhibitor MS-275 on apoptosis of human myeloma U266 cell line.
目的：探讨组蛋白去乙酰化酶抑制剂MS- 275诱导人多发性骨髓瘤细胞株u266凋亡的分子机制。
Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.
组蛋白乙酰化与基因转录等生物效应有密切的关系，组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
Histone is the nucleus of chromatin, the covalent modifications in its tails form the histone codes that regulate a number of biological processes.
组蛋白是染色质的核心，其尾部的共价修饰组成组蛋白密码，调节许多生物学事件。
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