The ultimate goal, then, is obvious. It is to block all of a tumour's avenues of genetic escape by developing drugs that deal with all the mutations that would allow such a break out.
那么，最终目标是明确的，那就是通过开发药物来堵住肿瘤基因逃跑的林荫大道，这些药物可以对付所有的可以引起暴发的变异。
First, it reads the genetic material in DNA adjacent to the break and makes a copy of it.
首先它能阅读邻近断裂的DNA内的遗传物质并复制它。
Some people even have a genetic defect in the enzymes in their liver that break down nicotine, whereby the mutant enzyme is much less effective at metabolizing nicotine than the normal variant.
有些人的肝脏中分解尼古丁的酶有遗传上的缺陷，因此这种突变的酶在代谢尼古丁时的作用就比正常的变异体的作用小。
Some people even have a genetic defect in the enzymes in their liver that break down nicotine, whereby the mutant enzyme is much less effective at metabolizing nicotine than the normal variant.
有些人的肝脏中分解尼古丁的酶有遗传上的缺陷，因此这种突变的酶在代谢尼古丁时的作用就比正常的变异体的作用小。
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