In short, SUMO helps the PRC1 complex repress genes, and SENP2 reverses this repression, allowing gene transcription and expression.
总之,相扑帮助PRC1复合体抑制基因,SENP2逆转这种抑制,使得基因转录和表达。
This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression.
这种现象主要在印迹基因和X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达,而去乙酰化则抑制基因表达。
Histone acetylation contributes to expression of gene, while histone deacetylation leads to repression of gene expression.
组蛋白乙酰化促进基因表达,而去乙酰化则抑制基因表达。
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