PacBio is in the process of introducing a game changing, new generation of sequencing technology.
PacBio是引入一个改变游戏规则，新一代测序技术的过程中。
The notion of high quality photos licensed for free was a game changing development in the stock photography market in 2000.
在2000年，高质量的图片免费许可使用在库存图片市场是一个改变游戏规则的举动。
While the features aren't as game changing as what the BIS 3.x releases may have been, 4.0 should still be a fairly decent stepping stone.
但是功能没有像已发行的BIS 3 .X版本一样带来重大改变，4.0应该仍然是一个相当不错的步进版本。
All of these companies share several common traits: strong visionary entrepreneurial roots, game changing impact and potential, and a struggle to cross the chasm into long term viability.
所有这些企业都有个共同的特征：企业内植根的强大梦想，有着改变游戏规则的影响力以及潜力，还有努力跨越鸿沟以形成长期的成长力的拼搏精神。
It's hard to stay ahead of the game in network security when the landscape is constantly changing.
当形势不断变化时，在网络安全领域保持领先地位是困难的。
Online marketplaces that connect importers and exporters are "really changing the whole game of how products are manufactured," says Shriftman. "Anyone can have anything made right now.
连接着进出口商的在线市场“真的改变了商品生产流通的整个游戏局面”，斯瑞夫曼表示，“现在，（通过在线市场）任何人可以得到任何他想要的。”
It's like the race organizers are changing the game rules in the middle of the season.
这就像是比赛主办单位在赛季中期更改了游戏规则。
We content providers must understand the changing game of distribution and make a mark to support the future of news-gathering that serves the public interest.
我们作为新闻内容供应商必须明白新闻传播竞赛规则的改变，让我们也做一点改变来支持服务公众利益的新闻采集业的未来。
This is an obvious case of double standards and changing the rules of the game AFTER the game has started.
这明显存在双重标准，在游戏开始之后改变游戏规则。
Those that argue that Cloud is just hype have already missed the bigger picture - the game is always changing and this is the next major change.
认为云计算仅仅是炒作的人已经错失了全景——游戏规则一直在改变，而云将成为下一个大变化。
Eschewing her game-changing acquisitions and grand strategies, Mr Hurd concentrated on operating efficiency, execution, financial performance and customers.
在他的带领下，惠普在关键时刻恢复振作起来。他摒弃前任改头换面的兼并收购，也不沿用其制定的宏伟策略，而是更加专注于提高公司效率和执行效果，注重财政状况以及客户需求。
They believed, correctly it turns out, that their designers could drop a game-changing phone into the market and "change the world" again.
他们毫无疑问地相信，他们的设计师能够用一款游戏持续改进的手机打入市场并且再次“改变世界！”
Now the BRICs—Brazil, Russia, India and China—are getting into the game, and changing it.
如今，金砖四国——巴西、俄罗斯、印度和中国，正在加入和改变这场角逐。
We know this is impossible right now, but we also know the kind of game-changing tools needed and the research agenda that will get us there.
我们知道，这在目前是不可能做到的，但是我们也明白，所需的那种改变游戏规则的工具以及将使我们达到目的研究议程。
Without tests, changing your code would be a guessing game.
如果不进行测试，修改代码就会象猜谜一样。
Then again, perhaps the quest for a cleaner environment shouldn't rely on the hunt for a game-changing technology.
也许对于清洁环境的追求，不应该仅仅指望某项能改变游戏规则的科技。
Below is the story of how OS X's game-changing interface came about. The story gives some insight into corporate creativity at Apple.
下面介绍OSX划时代的界面是如何产生的，这个故事让我们得以洞悉苹果的团队创造力。
The PHEV is seen as a game-changing technology that will have a major impact on our lives over the next several decades.
插电式混合动力车(PHEV)被看做是一项将在今后的几十年中对我们的生活有着重大影响的划时代的技术。
It can lead to the game-changing award of a penalty kick, probably the single most momentous refereeing decision in any sport.
跳水得到的奖励就是一个能改变比赛进程的点球，这也许是所有体育项目中意义最重大的一种判罚了。
But are hotels acknowledging this game-changing shift in communication?
但是酒店是否认识到这种沟通方式的转变？
The headline one is the new presidentialism of the campaign, most evident in the game-changing television debates, and also in the increased visibility of the leaders’ wives.
该现象得到大肆宣传。最为明显地体现该现象的，是扭转战局的电视辩论，以及更加频繁出现的领导人夫人。
"It is hard for investors to know the rules of the game because they keep changing," he says.
“投资者很难了解游戏规则，因为它们总在变，”他说。
If you aren't the first mover, and one of your competitors is steadily leaving you behind in their dust, changing the game is usually the best approach.
如果你不是先进者，而某位竞争对手已经一骑绝尘，将你远远抛在了身后，转行往往是最有效的做法。
Although that purchase shook many in the American film industry, it did not herald a transformation of Hollywood, nor did it prove a game-changing projection of Japanese cultural power.
尽管那次收购在美国电影界引起了巨大轰动，但却没有给好莱坞带去改变，也算不上是日本文化实力的转折点。
But this time we decided to join the fray in a way that could be game-changing - look at blogging as the foundation for a model of audience engagement.
但是这次我们决定以颠覆比赛规则的方式来做这事——将博客作为受众参与模式的基础。
We profile game-changing managers—the people making an impact with radical ideas.
我们描述了一写改变有些规则的管理者，这些人把“激进的想法”转化为一种爆发力。
It was first to market with a game-changing smart phone, but the company has pursued a high-end niche strategy with the iPhone that has left the door wide open for.
虽然首个向市场推出了改变游戏模式的智能手机，但该公司推出的iPhone却奉行高端“利基”(niche)战略，从而为Google攫取大众市场大留方便之门。
It was first to market with a game-changing smart phone, but the company has pursued a high-end niche strategy with the iPhone that has left the door wide open for.
虽然首个向市场推出了改变游戏模式的智能手机，但该公司推出的iPhone却奉行高端“利基”(niche)战略，从而为Google攫取大众市场大留方便之门。
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