Mutations in these genes could disrupt normal gene regulation and potentially affect the function of many other genes.
这些基因的变异能够扰乱正常基因调控并可能影响许多其他基因的功能。
These mutations, which occurred after the protein evolved its new function to bind to cortisol, would cause structural clashes within the protein if it were returned to its ancestral state.
在蛋白质进化到具有与皮质醇结合的新功能后产生的这些突变，如果蛋白质返回到原始状态，会导致其结构上产生冲突。
Mutations have altered the snake's receptor in such a way that, because the toxin cannot bind to the receptor, the acetylcholine function is undisturbed.
基因突变改变了这种蛇的受体，使得毒素无法致盲受体，乙酰胆碱的功能亦未受影响。
However, only a single copy of the gene is mutated in tumours, raising the possibility that the mutations do not result in a simple loss of function.
然而，在肿瘤中只有一个基因的单一复制出现突变，那就会增加突变的可能性而不仅仅是导致一个简单功能的丢失。
We evaluated the effect of location, coding type, and biophysical function of KCNQ1 mutations on the clinical phenotype of this disorder.
我们研究该疾病的不同临床类型与KCNQ1 基因变异的位置、编码类型、生物物理学功能的关系。
Topics covered include the analysis of mutations, and molecular analysis of the genes required for nervous system function.
涵盖的主题包括突变的分析和神经系统发挥功能所需基因的分子分析。
Furthermore, some patients with a rare, genetically inherited form of Parkinson's disease carry mutations in key genes that regulate mitochondrial function.
此外，少数基因遗传性的帕病病人在一些控制线粒体功能的关键基因上发生了基因突变。
The variants are small alterations in gene sequences - they are not mutations that destroy a gene's function.
在基因序列中这都是很小的变异——这种突变没有影响到基因的功能。
Chemistry high activity of free radicals can make the unsaturated fatty acid oxidation, making the cell function excessively, or recession mutations and proliferation and necrosis centralis disease.
化学活性高的自由基可使不饱和脂肪酸过度氧化，使细胞功能突变或衰退，引起组织增殖和坏死而产生置人于死地的疾病。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
原癌基因的突变导致的过度刺激细胞周期，而突变的肿瘤抑制基因，会导致在这一功能的控制过度活动。
They believe that mutations which have already been tied to metabolic disorders may also affect the way in which parts of the brain function.
他们相信已知与某些代谢疾病有关的突变基因也同样可能影响部分大脑运作。
In Crohn's disease, the proinflammatory state resulting from NOD2 mutations have been associated with a loss of antibacterial function of enterocytes such as paneth cells.
在克罗恩病中，由于NOD2基因突变导致的促炎症反应状态，已证实与肠细胞抗菌作用的丧失有关。
There are more than 600 silk worm mutations breeds in the gene pool bank of the Southweast University, which contains many traits concerning to production, genetical breeding and vital function.
在西南大学家蚕基因库中保存有600多种重要的突变体，许多与生产、遗传育种和重要的基因功能相关。
If we can change the function of non-corneal bone marrow stem cells by introducing them into human corneas, we can possibly repair the loss of visual sharpness caused by mutations.
如果将非角膜骨髓干细胞引入到人类角膜能够改变它们的功能，我们也许能够修复由于突变造成的视觉敏锐性的丧失。
It does not cover only process, function and location of genes, but also biomedical categories such as diseases, compounds, techniques and mutations.
它不仅覆盖了基因的过程、功能和定位，而且覆盖了生物医学分类，例如疾病、化合物、技术和突变。
This identified an unexpectedly high frequency of mutations involving genes that function as master regulators of normal B-cell development and differentiation.
他们确定了一个基因的意外高频突变，此基因是正常B细胞发生和分化的主要调节基因。
Then, both human and yeast cells were used to determine the effects of these mutations on protein function and cell viability.
然后，在人类和酵母细胞中检测了这些突变对于蛋白质功能和细胞生存能力的影响。
When you have two copies of a gene, useful mutations can arise that allow one or both genes to explore new functions while preserving the old function.
当你有一个基因的两个复制品时，有利改变可能就会出现，使一个或两个复制基因能够出现新的功能，并保留老的功能。
When you have two copies of a gene, useful mutations can arise that allow one or both genes to explore new functions while preserving the old function.
当你有一个基因的两个复制品时，有利改变可能就会出现，使一个或两个复制基因能够出现新的功能，并保留老的功能。
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