Objective: To explore the first-pass effect in Small intestine.
目的：探讨小肠在首过效应中的作用。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。
The objective of this study was to develop a good absorbed and stable preparation that can avoid the strong first-pass effect of nimodipine (NMD).
本文旨在寻找制备一个吸收良好、稳定性好、可避免尼莫地平强的首过效应的制剂。
Documents show that the low biological activity of quercetin is due to its low bioavailability. Poor solubility and first-pass effect are the main factors that affect its bioavailability.
文献表明槲皮素生物活性低是由于其低的生物利用度，溶解性差与首过效应是影响其生物利用度的主要因素。
Because of a serious liver first-pass effect, the dosage forms of Naloxone Hydrochloride is mainly used on domestic and aboard clinical practice in the forms of injection and sublingual tablet.
但由于该药肝脏首过效应严重，口服无效，目前国内外临床上供应用的盐酸纳洛酮的剂型为注射液和舌下片。
The only state to pass a bill requiring the vaccine for school entry is Virginia; it takes effect in October, after school begins, so will first apply in 2009.
弗吉尼亚州是唯一一个通过提案规定入学必须接种疫苗的州。该提案在十月份生效，那时学校已经开学，所以它首次应用将在2009年。
Objective To evaluate the characteristics of myocardial perfusion and therapeutic effect of acute myocardial infarction using first pass perfusion MR imaging.
目的采用MR首过灌注成像评价急性心肌梗死心肌组织血流灌注特点及治疗效果。
Objective To evaluate the characteristics of myocardial perfusion and therapeutic effect of acute myocardial infarction using first pass perfusion MR imaging.
目的采用MR首过灌注成像评价急性心肌梗死心肌组织血流灌注特点及治疗效果。
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