This research intended to construct a eukaryotic expression vector with a site-directed mutation of porcine MSTN propeptide gene.
本研究旨在构建具有猪 MSTN 前肽基因定点突变的真核表达载体。
"We already know that the over-expression or mutation of molecules known as NIK and TRAF3 in B cells is associated with human multiple myeloma," said Professor Mackay.
“我们已经知道，在B细胞过度表达或突变的NIK和TRAF3分子是与人类多发性骨髓瘤相关，”麦凯教授说。
The main application is in discovering new genes, analysis of gene expression, gene mutation, polymorphism and genetic sequence test.
主要应用于新基因发现、基因表达分析、基因突变及多态性分析、基因测序等。
Conclusion Construction of the eukaryotic expression vectors of wild type and mutant PRPF31 genes is basic work for research on the mechanisms of retinitis pigmentosa caused by PRPF31 mutation.
结论野生型和突变型PRPF31基因真核表达载体的构建，为研究PRPF31基因突变引起视网膜色素变性的机制奠定了基础。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达，但并不是通过基因突变或促进子甲基化而实现的，因此其失表达的机制还不清楚。
So people will try and get some sort of gene-based test to measure the expression-mutation of these kinases.
因此人们尝试着取得一些基因水平的测试蛋白激酶突变表达的方法。
Objective: To analyse the significance and relationship between p53 gene mutation and the expression of mutant type p53 gene protein in the laryngeal carcinomas.
目的：探讨喉癌P53基因突变与突变性P 53基因蛋白表达之间的相互关系及意义。
The positive cells expression of P53 had an important relation to the appearance of EBL. B cells with P53 mutation strain might be a target cell to format tumors.
EBL的发生与突变的P53蛋白过表达有重要关系，携带P53突变株的B淋巴细胞可能是形成肿瘤的靶细胞。
That may be a common physiological mechanism which means organism can control the expression of genes and resist the virus infection, or the DNA mutation induced by during the period of evolution.
在进化上，这可能是生物调控基因表达及抵御病毒侵染或转座子诱导DNA突变的一种共有的生理机制。
The mutation or abnormal expression of CHD gene is thought to be related to some human diseases.
CHD基因突变或表达异常与人类某些疾病有关。
Because it has been realized that cancer is not only a disease of defects in gene expression or mutation but also a metabolic disease in that cells need nutrients to grow.
因为人们已经认识到，癌症不仅仅是因一种基因表达或变异缺陷而导致的疾病，同时也似一种代谢性疾病，因为肿瘤细胞的生长需要营养物质。
Consumptive mutation expression is the mutation that consumes a concept, consume the mutation of the object, consume the mutation of means.
消费变异表现为消费理念的变异，消费对象的变异，消费方式的变异。
The expression of mutation P53 protein was related closely to histopathologic grade, tumor size, metastasis and prognosis of tumor(P<0.05), but it was not related to histologic types(P>0.05).
P53蛋白的阳性表达与组织学分级、肿瘤预后复发及肿瘤大小关系密切（P＜0．05），但与组织学类型无相关性（P＞0．05）。
To study the relationships between the expression level of PTEN gene, gene mutation and occurrence and development of glioma.
目的：探讨pten基因表达水平及其基因突变与脑胶质瘤的发生及恶性进展的关联性。
By the mean time, the technique have reported in the gene expression analysis, new gene discovery, gene mutation detection, SNP analysis, DNA re-sequence and diagnosis.
目前，该技术已用于基因表达谱分析、新基因发现、基因突变、基因多态性分析、药物筛选和基因测序及疾病的诊断。
This research intended to construct eukaryotic expression vector with a site-directed mutation of porcine MSTN propeptide gene, and verify its expression efficacy in C2C12 cells.
本研究旨在克隆通城猪含有第1个内含子的MSTN前肽基因，构建真核定点诱变载体，并通过转染C2C12细胞验证载体表达的有效性。
OBJECTIVE: Purpose to study the expression of P53 mutation protein, estrin receptor (er) and progestin receptor (pr) in mammary cancer and their relativity.
目的：探讨乳腺癌中P 5 3蛋白，雌激素受体(ER)，孕激素受体(PR)的表达及相关性研究。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
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