Objective to investigate the possibility of applying the DNA double strand break and apoptosis of lymphocytes to biological assay in radiation injury.
目的探讨受照后淋巴细胞DNA双链断裂和凋亡作为放射损伤生物学检测指标的可行性。
The NBS1 is a component of the MRE11/RAD50/NBS1 complex (MRN) and plays a critical role in the DNA double strand break (DSB) repair and the maintenance of chromosomal integrity.
NBS1作为MRE11/RAD50/NBS1复合物的组分之一,是细胞应答DNA损伤的一个关键蛋白质,在DNA双链断裂修复和维持基因组稳定中发挥重要的作用。
The results showed that the DR's DNA double strand break damage caused by heavy ion beams could be repaired through culture, and the repairing time extended as the increment of radiation dose.
结果表明,抗辐射菌经重离子射线照射后所引起的DNA二条链的切断损伤经过培养能被修复;切断的DNA二条链的修复时间随着照射剂量的增加而延长;
DNA double-strand break is probably the most lethal attack, with as little as one unrepaired DSB being capable of triggering programmed cell death.
DNA双链损伤是已知的最严重的细胞损伤,只要有一处未被修复的DSB就能引发程序性细胞凋亡。
Objective To observe the consistency of DNA double-strand break between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis(SCGE).
目的探讨整体照射与离体照射导致小鼠淋巴细胞DNA双链断裂的一致性,作为单细胞凝胶电泳技术应用于辐射生物剂量学的前期研究。
Objective To observe the consistency of DNA double-strand break between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis(SCGE).
目的探讨整体照射与离体照射导致小鼠淋巴细胞DNA双链断裂的一致性,作为单细胞凝胶电泳技术应用于辐射生物剂量学的前期研究。
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