The genotoxicity of arsenic, which includes the modification of DNA, DNA break damages and DNA repair prevention, may be the most important mechanism of arsenic carcinogenesis.
砷的致癌症机制主要有遗传物质修饰、DNA断裂损伤及活性氧生成等。
Scientists are mostly stumped as to how the radio frequency waves emitted by cellphones, which lack the punch to break chemical bonds or disrupt DNA, might cause cancer.
科学家们主要搞不懂的是,手机所释放的无线电波,连打断化学键或扰乱dna的冲击力都没有,又怎么可能导致癌症呢?
The nonionizing radiation given off by cellphones is too weak to break chemical bonds or damage DNA.
手机发出的非电离辐射很弱,不足以断开化学键或破坏DNA。
When the intended gene, which would have been inserted at the same time, comes along, the recombinase recognises it, and binds the DNA to the ends, repairing the break (see diagram).
当预期的可同时植入的基因出现时,承认它的重组酶,会把它固定在DNA的两端,开始修补DNA(见图)。
But here she was in a laboratory on a snowy day in January - while many of her peers across the country were still on winter break - inserting a piece of DNA into bacteria with a micropipette.
但是在大学纷飞的一月,和她一样在寒假里来自全国的同僚,正在正在显微镜下将一片DNA样本嵌入到细菌里。
Franklin's break came when she was hired by King's College in 1950 to work on the DNA project as a crystallographer—mapping the location of atoms within a structure.
1950年,富兰克林的机会来了,国王学院聘用她作为晶体绘制员参加DNA项目研究——她负责绘制一个结构内原子的位置图。
These damages can vary from a change to a single part of the DNA to a total break in the DNA structure.
这些损伤包括DNA单一部分的改变到DNA结构上的全部断裂的不同程度。
Objective to investigate the possibility of applying the DNA double strand break and apoptosis of lymphocytes to biological assay in radiation injury.
目的探讨受照后淋巴细胞DNA双链断裂和凋亡作为放射损伤生物学检测指标的可行性。
The young (12 weeks) and old (85 weeks) rats which were divided into three groups, were used to measure the DNA single chain break of liver nuclei and unscheduled DNA synthesis (UDS) of blood cells.
将其分为老年鼠对照组和药物组(85周龄)、青年鼠对照组(12周龄),以肝细胞核d na单链断裂数和全血细胞非程序dna合成(uds)为观察指标。
Objective To observe the consistency of DNA double-strand break between in vivo and in vitro irradiation, as a prophase study in radiation biodosimetry using single cell gel electrophoresis(SCGE).
目的探讨整体照射与离体照射导致小鼠淋巴细胞DNA双链断裂的一致性,作为单细胞凝胶电泳技术应用于辐射生物剂量学的前期研究。
Peroxynitrite, which is cytotoxic, can modify DNA bases and make DNA single strand break.
过亚硝酸根具有强细胞毒性,能够修饰DNA碱基、造成DNA单链断裂。
DNA double-strand break is probably the most lethal attack, with as little as one unrepaired DSB being capable of triggering programmed cell death.
DNA双链损伤是已知的最严重的细胞损伤,只要有一处未被修复的DSB就能引发程序性细胞凋亡。
Methods: the bactericidal mechanism of plasmas ozone against E. Coli on the surface was studied through observing change of ultramicrostructure, break of DNA double-strands and leakage of proteins.
方法:从超微结构、DNA链的断裂和蛋白质漏出三个方面研究等离子体臭氧对物体表面上大肠杆菌的杀灭机理。
The results showed that the DR's DNA double strand break damage caused by heavy ion beams could be repaired through culture, and the repairing time extended as the increment of radiation dose.
结果表明,抗辐射菌经重离子射线照射后所引起的DNA二条链的切断损伤经过培养能被修复;切断的DNA二条链的修复时间随着照射剂量的增加而延长;
First, it reads the genetic material in DNA adjacent to the break and makes a copy of it.
首先它能阅读邻近断裂的DNA内的遗传物质并复制它。
The NBS1 is a component of the MRE11/RAD50/NBS1 complex (MRN) and plays a critical role in the DNA double strand break (DSB) repair and the maintenance of chromosomal integrity.
NBS1作为MRE11/RAD50/NBS1复合物的组分之一,是细胞应答DNA损伤的一个关键蛋白质,在DNA双链断裂修复和维持基因组稳定中发挥重要的作用。
The NBS1 is a component of the MRE11/RAD50/NBS1 complex (MRN) and plays a critical role in the DNA double strand break (DSB) repair and the maintenance of chromosomal integrity.
NBS1作为MRE11/RAD50/NBS1复合物的组分之一,是细胞应答DNA损伤的一个关键蛋白质,在DNA双链断裂修复和维持基因组稳定中发挥重要的作用。
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