The principles also apply to drug substances and drug products covered in Type II drug master files (DMFs).

这些原则同样适用于二类DMF所涉及的原料药和制剂。

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Methods Subjects were 175 of 12~14 years old schoolchildren. DMFS, plaque scores and oral health behavior were recorded in baseline, year 1 and year 2 examinations.

方法对175名12～14岁儿童2年中新增龋与基线DMFS、口腔卫生行为、菌斑指数和牙菌斑中无机成分等指标进行纵向观察；

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Methods Subjects were 175 of 12~14 years old schoolchildren. DMFS, plaque scores and oral health behavior were recorded in baseline, year 1 and year 2 examinations.

方法对175名12～14岁儿童2年中新增龋与基线DMFS、口腔卫生行为、菌斑指数和牙菌斑中无机成分等指标进行纵向观察；

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