Dihydrolipoamide succinyltransferase (DLST) is a key subunit in this complex (2).
二氢硫辛酰胺-琥珀酰转移酶是复合物中的关键亚基(2)。
Mutations in the DLST gene may be responsible for the familial Alzheimer disease (1).
该基因的突变会导致家族性的阿尔茨海默病(1)。
Reduction of DLST increases the generation of reactive oxygen species production suggesting its role in oxidative stress (2).
DLST的数值减少会增加活性氧簇的产生,提示它可能在氧化应激中发挥作用(2)。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro188 of human DLST protein.
该单克隆抗体是由合成的人源dlst蛋白脯氨酸(188位)肽段免疫动物而制备的。
Deficiency of DLST in mice was suggested to cause increased oxidative stress in mitochondria and is involved in the pathogenesis of Alzheimer disease (2).
DLST缺失小鼠线粒体氧化应激增加,并且会导致阿尔茨海默病的发生(2)。
Research has shown that deficiency of DLST in mice is linked to increased oxidative stress in mitochondria, a process that may be involved in the pathogenesis of Alzheimer's disease (2).
研究表明,小鼠中DLST缺失与线粒体氧化应激的增加有关,并且会出现阿尔茨海默病的病理现象(2)。
Research has shown that deficiency of DLST in mice is linked to increased oxidative stress in mitochondria, a process that may be involved in the pathogenesis of Alzheimer's disease (2).
研究表明,小鼠中DLST缺失与线粒体氧化应激的增加有关,并且会出现阿尔茨海默病的病理现象(2)。
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