Objective To study the effect of water uptake on disintegration time of orally disintegrating tablet.
目的探讨口腔崩解片的吸水动力学过程对片剂崩解的影响。
Characteristic indexes such as appearance and disintegration time should be especially paid attention to in stability tests.
在稳定性研究中，尤应注意反映制剂特点的指标，如外观性状、崩解时限等。
Indomethacin enteric dispersible tablets were prepared, and factors affected disintegration time and dissolution rate were studied.
制备了吲哚美辛肠溶分散片，考察辅料对其崩解时限及溶出速度的影响。
METHODS: to take weight variation of pills, comprehensive quality and disintegration time limited as index, the above factors were observed by orthogonal test.
方法：以丸重差异、综合质量和溶散时限为评价指标，采用正交设计试验对各影响因素进行考察。
The characteristic constant of water uptake was compared with disintegration time in order to investigate the relationship between water uptake and disintegration.
将吸水特性常数与片剂崩解时间进行比较，考察水渗透与片剂崩解的关系。
The main factors that influence tablet hardness and disintegration time are wetting agent ethanol, agglutinating agent polyvinylpyrrolidone(PVP) and tablet pressure.
确定了制片压力、润湿剂无水乙醇和粘合剂聚乙烯吡咯烷酮为影响崩解时间和片剂硬度的主要影响因素。
Results the compound exhibited good flowability, packing rate, compressibility, and shorter disintegration time. It also improved the content uniformity of low dosage formulations.
结果复合辅料显示出较好的流动性、填充性、可压性和崩解性，低剂量片剂的含量均匀度符合要求。
Results the compound exhibited good flowability, packing rate, compressibility, and shorter disintegration time. It also improved the content uniformity of low dosage formulations.
结果复合辅料显示出较好的流动性、填充性、可压性和崩解性，低剂量片剂的含量均匀度符合要求。
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