Constitutive activation of the pathway involving these two genes appears to be a major contributor to the development of uveal melanoma. (Funded by the National Institutes of Health and others. ).
包含这两个基因的信号通路的组成性激活，可能是导致葡萄膜黑色素瘤的主要因素。
This signal pathway not only participates in regulating the development of the CNS, but also correlates with the neuron regeneration, development of glioma, and mental deficiency.
此信号通路不仅参与调节中枢神经系统的发育，而且与神经元再生、胶质瘤发生和精神发育迟缓等有关。
The success of the EGFR and VEGFR pathway antagonists in treatment of metastatic NSCLC has important implications for development of novel targeted therapies such as the PKC inhibitors.
EGFR和VEGFR途径拮抗剂在治疗转移性NSCLC中的成功对开发一种新的靶向治疗药物如PKC抑制剂具有重要意义。
The basal state of GA signaling is likely to be repressive and the GA signal seems to activate the pathway by de_repression to allow GA_stimulated growth and development.
GA信号传导通常处于抑制状态，GA信号通过去抑制作用激活该传导途径而促进GA刺激植物生长和发育。
The development of EGFR and VEGFR pathway antagonists has been blessed by a clear appreciation of the biology targeted by these therapeutic agents.
因EGFR和VEGFR途径拮抗剂具有明确的靶向生物学特性，这些药物的开发受到一致好评。
The results suggest that hole might be involved in heart development through MAPK signaling pathway.
研究表明，该基因可能通过参与MAPK信号途径而在心脏发育的过程中起作用。
Cholesterol biosynthetic pathway, status of research and development on inhibitors of key enzymes in cholesterol biosynthesis were reviewed.
综述了胆固醇生物合成过程及生物合成过程中关键酶抑制剂的研究开发现状。
Importantly, the growth of these parasites can be inhibited by the herbicide glyphosate, suggesting that the shikimate pathway will make a good target for the development of new anti-parasite agents.
重要的是，除草剂草甘膦可以抑制这些寄生虫的生长，表明莽草酸途径（shikimate pathway）可以成为开发一种新型抗寄生虫剂的好目标。
Meristematic nodules are tissues with distinct status during plant in vitro development and thus provide an important regeneration pathway via organogenesis.
分生结节是植物组织离体发育的一种特殊状态，也是一种有价值的植株再生途径。
This paper reviews the structure of CARP and its functional role during striated muscle development. The signal pathway involved in CARP expression, and the other members of MARP family.
本文综述了CARP基因与蛋白质结构、CARP的表达模式及其表达调控、参与调节CARP的细胞内信号转导通路、CARP在肌肉发育中的作用，以及MARP家族其他成员。
Then the author summarizes the shape and development of the idea of alienation since the modern times, and puts forward the pathway and the significance of this study.
然后对近现代以来科技异化观的形成与演进作了概述，并在此基础上提出本文的研究思路及意义。
This article reviews effects of UA on cancer cell proliferation signal transduction pathway and anti-vascular disease in order to provide some new ideas on the development of UA.
本文就UA对肿瘤细胞增殖信号通路的影响和抗心血管疾病作用研究进展方面进行综述，以期为UA的开发提供新思路。
The development of a patient pathway for screening, diagnosis, referral and treatment.
制定一套患者进行筛查、诊断、咨询和治疗的线路图。
With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.
随着对肿瘤发生机制研究的深入，作用于细胞信号转导通路的药物开始引起研究者的关注，成为抗肿瘤药物研发的重要靶点之一。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
We gave a brief introduction about the development of the immune pathway and effects of the mucosal immune in this article.
本文仅就近年来黏膜免疫的途径及效果的研究进展作一简要综述。
We also summarized the clinical trials of the mAbs blocking IL-6 pathway in development.
另外也对在研的IL - 6通路阻断单抗的临床试验结果进行了总结。
The researchers examined a gene called K13 that activates a pathway previously implicated in cancer development.
研究人员研究了一种称作k 13的基因，其可预先激活癌症产生过程中的一条途径。
These results demonstrate that CARD11 is a bona fide oncogene in DLBCL, providing a genetic rationale for the development of pharmacological inhibitors of the CARD11 pathway for DLBCL therapy.
这些结果表明在DLBCL中，CARD11是真正的癌基因，对DLBCL治疗中用药物抑制CARD11通路提供了遗传学理论。
These results demonstrate that CARD11 is a bona fide oncogene in DLBCL, providing a genetic rationale for the development of pharmacological inhibitors of the CARD11 pathway for DLBCL therapy.
这些结果表明在DLBCL中，CARD11是真正的癌基因，对DLBCL治疗中用药物抑制CARD11通路提供了遗传学理论。
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