• Objective: to study antibody dependent cell-mediated cytotoxicity (ADCC) on hepatocytes during immune response in halothane hepatitis of guinea pigs.

    目的:探讨氟烷性肝炎免疫应答中抗体依赖细胞介导的细胞毒作用(adcc)对肝细胞的毒性作用。

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  • NK cells, as the effectors in antibody-dependent cell mediated cytotoxicity, play important roles in anti-tumor immune response. They now have become the hot point in the study on tumor immunotherapy.

    NK细胞作为抗体依赖细胞毒作用的效应器,在抗肿瘤免疫中发挥着重要作用,成为目前肿瘤免疫治疗的研究热点。

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  • The cell lost its autotrophic character and became dependent on added chemical energy sources.

    细胞丧失了自养的特性,变成依赖于外加的化学能源生活。

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  • Themajor risk factors for perinatal transmission of HCV were shown to be dependent on peripheral blood mononuclear cell (PBMC) infection with HCV.

    围产期丙型肝炎感染的主要危险因素被证明是依赖于外周血中受hcv感染的单核细胞。

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  • The cell lost its autotroph ic character and became dependent on added chemical energy sources.

    细胞丧失了自养的特性,变成依赖于外加的化学能源生活。

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  • Methods Recipient's panel reactive antibody (PRA) was detected by using micro complement dependent lymphocytotoxicity test with Lambda cell tray.

    方法应用莱姆德细胞板通过补体依赖微量细胞毒性试验检测受者的群体反应性抗体(PRA) ;

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  • Although the reduction in trophoblast cell viability induced by PDG was dose-dependent Fig. 2, no such effect could be detected following treatment with LPS at varying concentrations Fig. 2c.

    PD G减少滋养层细胞活力的作用是呈剂量依赖性的如图2,但以不同浓度的LPS处理细胞时,我们并未发现其有减少细胞活力的作用。

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  • RESULTS Both DDP and VP16 obviously inhibited the lung cancer cell growth with dose and time dependent.

    结果不同浓度VP16和DDP对肺癌细胞生长均有明显的抑制作用,并有浓度和时间的依赖性。

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  • The replication of parvovirus is strongly dependent on cellular factors associated with proliferation and differentiation, especially those related to the S-phase of the cell cycle.

    细小病毒的复制紧紧依赖于和增殖及分化有关的细胞因子,尤其是和细胞周期S-期有关的因子。

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  • It is suggested that the well-being of each individual cell is dependent on the adequacy of its environment to furnish nutrition and carry away metabolites.

    据认为各个细胞的健康取决于周围环境对它供应充足的营养物质并能运走其代谢产物。

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  • CONCLUSION: GLM could enhance the cytotoxic effect of ADM on drug resistant cell and increase intracellular drug concentration in a concentration dependent fashion.

    结论:GLM提取物可提高了ADM对耐药细胞的细胞毒作用,增加了耐药细胞内药物浓度,且呈剂量依赖性。

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  • AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independent prostate cancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.

    目的:利用RNA干涉技术抑制雄激素受体(AR)的表达,研究AR在激素依赖性和激素非依赖性前列腺癌细胞增殖中的作用。

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  • The present study indicates that interferon can suppress cancer growth by inhibiting expression of a cancer-dependent transcription factor that controls genes that regulate cancer cell growth.

    本研究表明,干扰素可以通过抑制肿瘤依赖性转录因子的表达来达到抑制肿瘤的作用,这种转录因子可以调控肿瘤细胞的生长。

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  • Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.

    细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶(CDK)复合物来调控。

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  • The effect of thymic peptide hormone on the changes of PNA receptors on the cell surface of mouse thymocyte was found to be both concentration and time dependent.

    我们研究了胸腺激肽与胸腺细胞的温育时间、不同剂量及酸、碱、热和酶处理后的胸腺激肽对PNA受体的影响。

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  • All the results above shows that EDF has an inhibitory effect on the proliferation of tumor cells and the effect is cell type dependent as well as dose-dependent.

    以上结果证明了EDF对恶性细胞具有增殖抑制作用。这种作用对不同种类细胞敏感性不同,并且与剂量呈正相关。

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  • VEGF secretion by cyst lining epithelial cell was reduced by CXB in a concentration and time-dependent manner.

    CXB可减少囊肿衬里上皮细胞VEGF的分泌,而且抑制作用具有时间、浓度依赖性。

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  • Objective To investigate the relationship between IL 6 signal transduction and its biological function on a human IL 6 dependent myeloma cell line XG 7.

    目的研究白细胞介素6 (IL 6 )依赖型人骨髓瘤细胞系XG 7中IL 6信号转导途径活化与生物学效应之间的关系。

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  • The phenomenon of "2-cell block" is strain dependent, and is maternally restricted by cytoplasm.

    小鼠的2 -细胞阻滞现象受细胞质内母型物质制约,具有品系依赖性。

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  • Promoter activity and protein fusions of PLT homologues display gradient distributions with maxima in the stem cell area. PLT activities are largely additive and dosage dependent.

    本文中我们把根系形成必需的四种PLT同源族用进化枝表示出来,启动子活性及PLT蛋白融合显示出在干细胞上最大的坡度分布。

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  • Results Venenum Bufonis had growth inhibitory and apoptosis-inducing effects on U2OS cell with a time and dose dependent relation.

    结果蟾酥水提取物对U2 OS细胞具有生长抑制及诱导凋亡作用,且呈时间依赖和剂量依赖。

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  • It USES feature dependent graph as data model, cell-based model as geometric model, and view model as user interface, but it is more complex than the former system based on parameter and history.

    在底层它用特征依赖图作为数据模型,在中层用细胞元模型作几何模型,在用户层用视图模型表示。

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  • Using the whole-cell patch-clamp technique, clear evidence was provided for the existence of a hitherto unreported, voltage-dependent nonselective cation current (NSCC) in rabbit ventricular myocytes.

    应用全细胞膜片钳制技术,我们首次报道了在兔的心室肌细胞存在一种电压依赖性的非特异性阳离子流(NSCC)。

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  • Surface GalTase also delivers a growth inhibitory signal by modulating the ability of the EGF receptor to transduce EGF dependent signals, and plays an important role during cell growth.

    另外,表面半乳糖基转移酶通过调节表皮生长因子受体信号传导能力向胞内传递生长抑制信号,在细胞增殖控制中起重要作用。

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  • The transformation probability for the neighborhood sites of a recrystallization grain is dependent on the growth velocity and the cell shape.

    根据动态再结晶晶粒生长速度和与其相邻基元形状确定转变概率。

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  • The erythrocyte ATP and NAD contents showed a cell-age dependent decrease , while no such changes happened in their ADP, AMP and NADP contents.

    结果表明,正常人红细胞内ATP含量和NAD含量随细胞老化而降低,但ADP、AMP,和NADP含量的改变不明显;

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  • TB induced endothelial cell contraction appeared in a time -dependent pattern.

    TB使内皮细胞发生收缩,细胞收缩程度具有时间依赖性。

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  • They found that the asymmetric activation of one EGFR kinase domain by another is analogous to the activation of cyclin-dependent kinase (CDK) by cyclin, which are involved in regulating cell growth.

    他们发现,由一个分子对另外一个EGFR激酶结构域的不对称激活类似于涉及调控细胞生长的细胞周期蛋白激活细胞周期蛋白依赖型激酶的方式。

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  • Both DDP and QU inhibited the proliferation and induced the apoptosis of SGC7901 cells in a time and concentration-dependent manner. QU combined with DDP synergistically enhanced cell death.

    DDP和QU均可以抑制胃癌SGC - 7901细胞增生或诱导其凋亡,且有时间和剂量依赖效应,联合应用具有协同效应。

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  • These compounds were assayed for inhibitory activity against A549 lung cancer cell growth, and the inhibitory effects on the cell viability were dose-dependent.

    所得化合物均具有抑制A549肺癌细胞生长的活性,其抑制效果具有浓度依赖性。

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