Conclusions VMC can be caused in mice after CVB3 inoculation, abnormal cardiomyocyte apoptosis can be found in VMC.
结论实验组小鼠在接种CV B3后可引起VMC, VMC中存在异常的心肌细胞凋亡现象。
Conclusion CVB3-induced myocarditis is probably associated with genes expression profiles of certain ECM components.
结论急性柯萨奇病毒性心肌炎的发病与某些ECM成分基因表达异常有关。
Objective To investigate the sequence and variation of VP4 and 3D gene of a coxsackievirus B3 Chinese isolate(CVB3-Chi).
目的研究柯萨奇B组3型病毒（CVB3）中国分离株结构蛋白VP4、非结构蛋白3D基因序列及变异性。
Objective to study the effects of SMBY on the viral myocarditis mices infected CVB3 and to explore its possible mechanism.
目的：观察生脉保元汤对柯萨奇B3病毒性心肌炎小鼠的影响并初步探讨其作用机制。
Objective To construct a bivalent VP1 gene vaccine against Coxsackie virus B1 and B3 (CVB1 and CVB3) and to test its immunogenicity in mice.
目的构建柯萨奇病毒（CV）B1/B3型二价VP1基因免疫质粒，并探讨其免疫原性。
Objective To investigate the role of monocyte chemoattractant protein 1(MCP 1) in viral myocarditis (VMC) induced by coxsackievirus Group B Type 3 (CVB3).
目的研究单核细胞趋化蛋白-1（MCP- 1）在B3型柯萨奇病毒（CVB3）诱导病毒性心肌炎（VMC）发病中的作用。
Though CVB3 vaccine can inhibit CVB3B3myocarditis, but it needs mass viral antigen while preparing, so the cost is too high to popularize and use in a large amount.
CVB3疫苗虽然可以抑制小鼠的CVB3心肌炎，但制备时需要大量的病毒抗原，成本过高，难以推广及大量使用。
Objective To study the effects of bupleurum root, scutellaria root and baked licorice respectively, on viral myocarditis caused by coxsackievirus B3 (CVB3) in mice.
目的探讨单剂柴胡、黄芩、炙甘草对柯萨奇病毒B3 (CVB3)感染的病毒性心肌炎小鼠的治疗作用。
The results indicate that administrations of non-cytotoxic concentrations of orlistat reduced the replication of coxsackievirus B3 (CVB3) in different cell types significantly.
结果表明，非细胞毒性浓度的奥利司他减少了柯萨奇病毒B3 (CVB3)在不同的细胞类型的复制。
Purpose To investigate the role of monocyte chemoattractant protein-1(MCP?1) in viral myocarditis (VMC) induced by coxsackievirus group B type 3 (CVB3) and its mechanism in pathogenesis of VMC.
目的研究单核细胞趋化蛋白1（MCP1）在B3型柯萨奇病毒（CVB3）诱导病毒性心肌炎（VMC）发病中的作用及其机制。
Ratio of mouse heart weight versus body weight (HW/BW), myocardial tissue pathological score of cardiac tissue (PS), the level of CK MB in serum and CVB3 loading of myocardial tissue were analyzed.
比较各组小鼠心脏重量和体重的比值（HW/BW）、心肌组织病理学积分（PS）、心肌组织病毒载量、血清CK-MB水平。
Ratio of mouse heart weight versus body weight (HW/BW), myocardial tissue pathological score of cardiac tissue (PS), the level of CK MB in serum and CVB3 loading of myocardial tissue were analyzed.
比较各组小鼠心脏重量和体重的比值（HW/BW）、心肌组织病理学积分（PS）、心肌组织病毒载量、血清CK-MB水平。
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