They then armed it with a gene encoding a protein called GM-CSF, which triggers an immune attack against cancer cells.
然后将GM - CSF蛋白质植入其中一组基因,这能触发针对癌细胞的免疫性攻击。
Another protocol, sometimes referred to as "dose escalated" 3f8, combines 3f8 with GM-CSF.
另一种方案,有时被指是“渐增剂量”的3f 8与GM - CSF的组合。
The USF Health Byrd Alzheimer's Institute plans to begin a pilot clinical trial later this year investigating GM-CSF (Leukine) in patients with mild or moderate Alzheimer's disease.
USF的健康伯德阿尔茨海默氏症学会计划在今年末要开展一项涉及调查重组GM-CSF在轻度或中度阿尔茨海默病人中应用的临床试验。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
The researchers suggest that GM-CSF boosted during the immune system overdrive of rheumatoid arthritis helps harness the beneficial properties of inflammation in the brain.
研究人员表明当风湿性关节炎中免疫系统过度反映时,GM-CSF的产生可以帮助利用脑中炎症发生时有益的物质。
The goblet cells in small bronchi were identified with AB-PAS staining, and the expression of GM-CSF in the same airway was assessed with immunohistochemistry staining.
AB PAS特染法检测哮喘小鼠小支气管杯状细胞的分布;同一解剖部位采用免疫组化染色法检测GM CSF的表达。
Conclusion GM-CSF gene immunization can induce antitumor effects and may be a novel approach to tumor therapy in future.
结论:GM - CSF基因免疫能诱发小鼠抗肿瘤作用,肌肉注射比皮下注射效果好。
Objective This article investigated the antitumor effects mediated by naked DNA coding human FL and GM-CSF.
目的探讨可表达人FL和GM - CSF的裸dna抑制小鼠移植肿瘤生长的作用。
Conclusion IL-6and GM-CSF may be involved in the autoimmune mechanism of non-segmental type of vitiligo.
结论IL鄄6和GM鄄CSF在非节段型白癜风自身免疫机制中可能起一定作用。
AIM: To compare the therapeutic effect, adverse reactions and the costs between GM-CSF and G-CSF in treating leucopenia in chemotherapy of cancer.
目的:观察灵杆菌素、惠尔血治疗化疗病人白细胞下降的疗效、不良反应及成本—效果对比。
Conclusion Local application of GM-CSF gel is able to promote diabetic wound healing in mice by inducing re-epithelization and collagen metabolism in the wound sites.
结论糖尿病小鼠创面外用GM-CSF凝胶,可诱导创面再上皮化和胶原蛋白合成,从而促进创面愈合。
Diagnosis was based on analysis of irradiation doses, clinical manifestations and laboratory results. In therapeutical aspect, GM CSF was administered on the basis of comprehensive treatment.
临床诊断根据患者受照剂量,临床表现和实验室结果进行综合分析,治疗上在对症治疗和综合治疗的基础上,应用了美国生产的GM - CSF。
Methods:Animol models were made which have intestinal dysbacteriosis caused by antibiotics. Test the level of IL-3 and GM-CSF by ELISA.
方法:采用抗生素脱污染造成小鼠肠道菌群失调的动物模型,用ELISA的方法检测血清白细胞介素3(IL 3)、粒巨噬细胞集落刺激因子(GM CSF)的含量。
Conclusion: GM-CSF gene transfered tumor vaccine in RMA tumor model induced better antitumor immune effect and will be a novel approach to ca ncer in the future.
结论:在RMA肿瘤模型中,GM - CSF基因转导的肿瘤细胞瘤苗有较好的抗肿瘤免疫效果,此法有可能成为治疗肿瘤的有效途径。
Methods: the experimental subjects were divided into GS group, control group and GM-CSF group. FACs technology had been used to determine the apoptosis ratio.
方法:实验分人参皂甙组、对照组和GM - CSF组,采用流式细胞技术测定各组细胞的凋亡率。
The above results showed efficiency of vaccination with mitomycin-C inactivated FBL-3-GM-CSF into mice and feasibility of immune therapy of leukemia.
以上研究结果显示出丝裂霉素灭活fb卜3一gm一csf后作为瘤苗的有效性和白血病免疫治疗的可行性。
Addition of GM-CSF did not impair tolerance to rituximab, and adverse events were rare and mild.
添加GM-CSF不减弱美罗华的耐受性,不良反应很少,并且很轻。
The second one is to segment brain MR images into different tissue classes, namely, gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF).
脑组织分类,即将脑部MR图像标记为灰质、白质与脑脊液三种不同的组织区域;
In addition, the result of receptor binding sites analysis suggested that G2 had the structural capability to bind two GM CSF receptors simultaneously.
另外,从受体结合位点的分析结果来看,g2分子在结构上有能力同时结合两分子的GMCSF受体。
Objective: to evaluate the effect of granulocyte macrophage colony stimulating factor (GM CSF) on the growth of the ovarian carcinoma cell lines.
目的:了解粒细胞巨噬细胞集落刺激因子(GMCSF)对人卵巢癌细胞株生长的影响。
GM CSF could maintain the survival of normal PMN, but not for SIV infected PMN.
GM CSF对正常PMN的存活有一定程度的维持作用,但对SIV感染PMN不起明显作用。
GM-CSF promotes human vascular endothelial cells to form vessel-like structure in vitro in a dose-dependent and time-dependent manner.
GM - CSF可以促进体外诱导人血管内皮细胞血管形成,并在一定范围内呈剂量及时间依赖效应。
GM-CSF promotes human vascular endothelial cells to form vessel-like structure in vitro in a dose-dependent and time-dependent manner.
GM - CSF可以促进体外诱导人血管内皮细胞血管形成,并在一定范围内呈剂量及时间依赖效应。
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