Ciwujia capsule can protect the colon tissue of depressed rats by changing the levels of MDA, SOD and the expression of COX 2.
刺五加胶囊可能通过改变抑郁模型大鼠结肠组织mda,SOD和COX 2的表达来改善其结肠的功能。
Objective To explore the expression of cyclooxygenase 2 (COX 2) alternative splice variant in human colon cancer tissue and its possible significance.
目的探讨人结肠癌组织中是否存在环加氧酶2 (COX 2)选择性剪接异构体的表达及其可能意义。
In recent animal studies, this chemical inhibited COX-2, a protein that spurs inflammation (the same protein that so-called COX-2 inhibitor drugs such as Celebrex quash).
在最近的动物研究中，这种化学物质抑制了COX - 2(环氧化酶)——引发炎症的一种蛋白质(相同的蛋白质称为COX - 2抑制剂，药物如西乐葆则则无效)。
COX-2 inhibitors are powerful anti-inflammatories, but synthetic forms of COX-2 inhibitors have caused numerous side effects.
COX-2抑制剂是种非常有效的抗炎物质，但是人工制造的COX-2抑制剂会导致许多的副作用。
The drugs include traditional non-steroidal anti-inflammatory drugs (NSAIDS) as well as new generation anti-inflammatory drugs, known as COX-2 inhibitors.
这类药物包括传统的非甾体抗炎药（NSAIDs），以及新一代抗炎药，通称COX- 2 抑制剂。
Nor does it mean that COX-2 inhibitors, which repress COX-2 activity, will necessarily lead to weight gain.
也不意味着COX - 2抑制剂，抑制COX - 2活性，就必然会导致体重增加。
Since then, there has been much debate about the cardiovascular safety of COX-2 inhibitors and traditional NSAIDs, which several studies have not been able to resolve.
此后，COX - 2抑制剂和传统的NSAIDs在心血管安全性方面一直备受争议。
Objective to investigate the expression of COX-2 and its relation to clinical pathophysiological features and prognosis in non-small cell lung cancer (NSCLC).
目的探讨非小细胞肺癌组织中COX 2的表达情况及其与患者临床病理生理特征和预后的关系。
Objective To study the expression of cyclooxygenase-2 (COX-2) and HER-2 in human breast cancer and their relationship.
目的研究环氧化酶2 (COX 2)和表皮生长因子2 (HER 2)在乳腺癌中的表达及其相关性。
Objective To investigate the expression of Cyclooxygenase-2 (COX-2) and its prognostic significance in oral squamous cell carcinoma.
目的调查环氧化酶- 2 (COX - 2)在口腔鳞状细胞癌中的表达及其预后意义。
Similar to immortal cells, the majority of breast cancer cell lines expressed low levels of COX-2 protein.
与这些细胞相似的是，COX - 2在绝大多数乳腺癌细胞系仅有很低程度的表达。
Recent studies implicated expression of cyclooxygenase 2 (COX-2) as a marker to identify precursor cells for breast cancer.
最近的一些研究表明环氧化酶2 (COX - 2)的表达可以作为发现乳腺癌细胞的标记。
Objective: To investigate the expression of COX-2 and MMP-7 and their influence on invasion and metastasis in colorectal cancer.
目的：探讨结直肠癌环氧化酶- 2和基质金属蛋白酶- 7的表达与侵袭、转移的关系。
Conclusion The patients with COX-2 positive expression possibly have axillary lymph node metastases of breast cancer.
结论：COX - 2阳性表达的患者可能易发生乳腺癌腋窝淋巴结转移。
OBJECTIVE: To explore the relationship between the expression of COX-2 and pathophysiological features of patients with lung cancer.
目的：探讨肺癌组织中COX - 2的表达及其与临床病理生理特征之间的关系。
Methods The expression of COX-2 was determined by immunohistochemistry in 45 cases of malignant melanoma and 25 intradermal nevi .
方法免疫组化法比较性研究25例皮内痣、45例恶性黑素瘤COX-2蛋白的表达情况。
A reduction for the risk of COX-2-positive tumors was found with increasing duration of aspirin use (multivariate relative risk 0.59), becoming evident after 10 years, the researchers said.
研究发现增加期服用阿斯匹林时间可以减少肿瘤中COX - 2阳性的风险(多元相对危险度0.59)，10年后越来越明显，研究人员说。
However, patients with a prior MI may be at increased risk for experiencing another if they use either COX-2-selective inhibitor, the research indicates.
然而，研究显示如果心梗病人使用任何一个选择性COX- 2抑制剂都会增加再次心梗的几率。
Objective: To explore the relationships between COX - 2 expression and angiogenesis in oral malignant melanoma.
目的探讨环氧化酶-2（COX-2）表达和口腔恶性黑色素瘤血管生成的关系。
In contrast, with absent or weak COX-2 tumors, regular or nonregular use of aspirin made no difference.
相反，COX - 2不表达或表达较弱的肿瘤，定期或不定期使用阿斯匹林没有差别。
ResultS COX - 2 protein induction paralleled temporally and overlapped anatomically the appearance of TUNEL - positive cells in ischemic penumbra.
结果环氧酶-2蛋白的表达与TUNEL阳性细胞在时程上一致，解剖部位上重叠。
Objective To study the expression of cyclooxygenase -2 (COX-2) in skin carcinoma and its clinical significance.
目的探讨环氧合酶2 (COX 2)在皮肤肿瘤组织中的表达及其临床意义。
Another limitation, they noted, was the lack of a standardized classification system for COX-2 expression in colorectal cancer.
他们指出，另一个限制因素是，对COX- 2在大肠癌中的表达缺乏一个规范的分类体系。
Objective To explore the effect of cyclooxygenase 2 (COX-2) in the pathogenesis of alcoholic liver disease (ALD).
目的探讨环氧合酶2 (COX - 2)在酒精性肝病(ALD)发病机制中的作用。
Aim: To study the effect of chronic hypoxic hypercapnia on expression of COX-2 mRNA in pulmonary arterioles.
目的：研究慢性低氧高二氧化碳对大鼠肺动脉环氧酶- 2 (COX - 2)基因表达的影响。
Aims To investigate the relationship between COX-2, VEGF expressions and the clinical pathologic characteristics of gastric carcinoma.
目的：探讨COX - 2和vegf的表达与胃癌临床病理特征之间的关系以及COX - 2与VEGF表达的相关性。
COX-2 expression is obviously increased in skin tumor and played an important role in proliferation, differentiation and metastasis of skin tumor.
COX - 2在皮肤肿瘤中表达明显上调，且在皮肤肿瘤的增殖、分化及转移中起着重要作用。
However, it was recently shown that the reproductive defects of COX-2-deficient mice mainly depend upon genetic background of the mouse strains.
最近的研究表明，COX-2基因敲除小鼠的生殖缺陷主要依赖小鼠的遗传背景，与小鼠的品系相关。
Regular use of aspirin appears to reduce the risk of colorectal cancers that oerexpress COX-2 but not the risk of colorectal cancers with weak or absent expression of COX-2.
结论：定期口服阿斯匹林显示能降低COX-2过度表达的结直肠癌的风险，但不能降低COX-2弱或无表达的结直肠癌的风险。
Regular use of aspirin appears to reduce the risk of colorectal cancers that oerexpress COX-2 but not the risk of colorectal cancers with weak or absent expression of COX-2.
结论：定期口服阿斯匹林显示能降低COX-2过度表达的结直肠癌的风险，但不能降低COX-2弱或无表达的结直肠癌的风险。
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