OBJECTIVE: To study the identification problems of pharmacokinetic compartment models.
目的:研究药动学房室模型的辨识问题。
The plasma concentration-time curves of cryptotanshinone were best fitted with one-compartment and two-compartment models for cryptotanshinone and tanshinones extract of Salvia miltiorrhiza Bge.
大鼠灌胃隐丹参酮和丹参酮提取物后的药-时曲线分别符合一房室和二房室模型。
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
参数法包括十个药动学模型和三种药效学模型,可以同时求算药动学和药效学参数;
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
参数法包括十个药动学模型和三种药效学模型,可以同时求算药动学和药效学参数;
应用推荐