Patients at risk for heart attacks or strokes who use clopidogrel to prevent blood clots will not get the full effect of this medicine if they are also taking omeprazole.
心脏病发作或中风的高危患者应用氯吡格雷预防血凝块，若同时服用奥美拉唑，药效就会大打折扣。
All patients were pretreated with aspirin and clopidogrel.
所有病人治疗前都在服用阿司匹林和氯吡格雷。
Of 804 patients, 105 (13%) were not responsive to clopidogrel.
在804名患者中有105位(13%)对氯吡格雷无效。
Is the time now right for selective gene profiling in clopidogrel patients?
是时候对氯吡格雷治疗患者选择性检测基因谱吗？
The invention also provides a preparation method of the clopidogrel bisulfate tablet.
本发明还提供了所述的硫酸氢氯吡格雷片剂的制备方法。
The invention relates to a preparation process of clopidogrel bisulfate solid preparation.
本发明涉及硫酸氢氯吡格雷固体制剂的制备工艺。
OBJECTIVE: To provide information for clinical rational usage of ticlopidine and clopidogrel.
前言： 目的：为临床合理使用噻氯吡定和氯吡格雷提供参考。
Objective To investigate the therapeutic effect of clopidogrel on progressive ischemic cerebral apoplexy.
目的研究氯吡格雷治疗进展型缺血性脑卒中的疗效。
Experiment results show that the stability of the clopidogrel bisulfate tablet of the invention is excellent.
实验表明，本发明的硫酸氢氯吡格雷片剂的稳定性优异。
Objective To investigate the clinical effect of two kinds of clopidogrel on percutaneous coronary intervention.
目的观察两种硫酸氢氯吡格雷在经皮冠状动脉介入治疗中的临床应用效果。
The invention relates to a bisulfate clopidogrel solid preparation, particles and a preparation method thereof.
本发明涉及一种硫酸氢氯吡格雷的固体制剂、其颗粒及其制备方法。
Preferred drugs in the order: first choice as clopidogrel, to aspirin second choice, third choice as ticlopidine.
优选药物的次序为：第一选择为氯吡格雷，第二选择为阿司匹林，第三选择为噻氯匹啶。
Conclusion The PPI esomeprazole has no significant influence on inhibition of platelet aggregation by clopidogrel.
结论未发现埃索美拉唑对氯吡格雷的抗血小板聚集作用产生明显影响。
Cigarette smoking induces CYP1A2 and may, therefore, enhance the conversion of clopidogrel to its active metabolite.
吸烟诱导CYP1A2而且可能因此增强氯吡格雷转化为其活性代谢产物。
Objective to observe the influence of proton pump inhibitor (PPI) esomeprazole on antiplatelet effect of clopidogrel.
目的观察质子泵抑制剂埃索美拉唑是否影响氯吡格雷的抗血小板聚集作用。
Study Question: What is the evidence that a platelet rebound exists, and can it be attenuated by clopidogrel tapering?
研究问题：血小板反跳存在的证据是什么？它能通过氯吡格雷逐渐停药而减弱呢？
Those assigned to clopidogrel received a 300-mg loading dose before PCI, followed by a maintenance dose of 75 mg daily.
被安排给予氯吡格雷的患者，在PCI前的负载量为300mg，之后的维持剂量为每天75mg。
To investigate the relationship between the recurrence of ischemic events and clopidogrel resistance in 1 month after CS.
观察CS术后1个月复发缺血事件与氯吡格雷抵抗的关系。
Patients undergoing stent-based PCI should be treated with triple therapy consisting of aspirin clopidogrel and warfarin.
植入支架的PCI患者应该应用阿司匹林、氯吡格雷和华法林三联治疗。
Objectives: We hypothesized that a standardized outpatient clopidogrel desensitization protocol would be safe and effective.
目的：我们假设门诊病人标准化氯吡格雷脱敏疗法是安全且有效的。
On the other hand, the double dose clopidogrel and high-dose aspirin combination seemed to result in the lowest event rates.
另一方面，氯吡格雷双倍剂量联合大剂量阿司匹林似乎事件发生率最低。
Objectives: the purpose of this study was to examine the effect of cigarette smoking on the platelet response to clopidogrel.
目标：本研究的目的是探讨吸烟对血小板对氯吡格雷反应的作用。
Objective to observe the influence of rosuvastatin or atorvastatin on platelet aggregation in patients treated with clopidogrel.
目的观察瑞舒伐他汀和阿托伐他汀对氯吡格雷抗血小板活性的影响。
The blood platelet aggregation is a simple, effective and practical platelet function experiment for the clopidogrel dosage monitor.
提示血小板聚集试验为氯吡格雷剂量监测简捷、实用、有效的方法之一。
As a result, studies have shown that when clopidogrel and omeprazole are taken together, the effectiveness of clopidogrel is reduced.
因此，多项研究表明当氯吡格雷和奥美拉唑同时给予时，氯吡格雷的疗效降低。
Recent mechanistic studies, however, suggest that omeprazole may reduce the inhibitory effect of clopidogrel on platelet aggregation.
然而已有机制研究提出奥美拉唑会降低氯吡格雷抗血小板的疗效。
Objective: To observe the clinical effect and safety in treatment of non-ST elevation myocardial infarction (NSTEMI) with clopidogrel.
目的：观察氯吡格雷治疗急性非st段抬高心肌梗死(NSTEMI)的临床疗效及安全性。
Objective: To observe the clinical effect and safety in treatment of non-ST elevation myocardial infarction (NSTEMI) with clopidogrel.
目的：观察氯吡格雷治疗急性非st段抬高心肌梗死(NSTEMI)的临床疗效及安全性。
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