Comet assay and sperm chromatin structure assay showed no significant change.
彗星实验和染色质结构分析则无明显变化。
The second purpose is to change chromatin structure and, hence, the physical interactions between histones and DNA.
第二个目的是为了改变染色质结构以及组蛋白与DNA之间的物理相互作用。
Many events such as the alteration of chromatin structure, the interaction between cis-elements and trans-factors are involved in this process.
它涉及到染色体结构的改变、顺式作用元件和反式作用因子相互作用等多种过程。
Lamin proteins are thought to determine the size and shape of cell nuclei and to be involved in nuclear stability, chromatin structure and gene expression.
型核纤层蛋白决定细胞核的大小及形状，与细胞核的稳定性、染色质结构以及基因表达有关。
These modifications serve to alter chromatin structure and accessibility, and to act as docking sites for transcription factors or other histone modifying enzymes.
这些修饰为改变染色质结构和易接近性服务，并作为转录因子或其他组蛋白修饰酶的停靠位点。
Their presence on histones can dictate the higher-order chromatin structure in which DNA is packaged and can orchestrate the ordered recruitment of enzyme complexes to manipulate DNA.
它们在组蛋白上的出现能够提示更高阶的染色质结构，DNA包装在该结构中，且能够精心安排酶复合物的有秩序的招募来调控DNA。
We will discuss the importance of chromatin structure in contemporary modeling, and review recent research results on the relationship between chromatin structure and transcriptional regulation.
我们会讨论在当代的模型化里染色质结构的重要性，并且温习在染色质结构和转录调控之间关系上，当前的研究工作成果。
The researchers began their work with the goal of learning how two different methylation marks affect the overall structure of nucleosomes and chromatin.
研究人员怀着了解两种不同的甲基化标记怎样影响核小体和染色质结构的目的开始工作。
With this new set of tools, Luger and her colleagues did X-ray crystallographic and biophysical studies to see how methylation affects the structure of chromatin and nucleosomes.
利用这种新型工具，Luger和他的同事进行了X射线晶体学和生物物理学研究，来看甲基化怎样影响染色质和核小体结构。
The regulation at both DNA level and chromatin level happen in the nucleus and are closely related to the nuclear structure.
DNA水平和染色体水平上的调控都是在细胞核内发生的，那么就与核内的复杂结构密不可分。
Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.
组蛋白乙酰化和去乙酰化可以改变染色质的结构，参与基因的表达调控和重编程。
Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.
组蛋白乙酰化和去乙酰化可以改变染色质的结构，参与基因的表达调控和重编程。
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