Montelukast, a Selective Cysteinyl Leukotriene Receptor 1 Antagonist, Reduces Cerulein-Induced Pancreatic Injury in Rats.
孟鲁司特，选择性白三烯受体1拮抗物，能减少雨蛙肽诱导的胰腺损害。
By peritoneal injection of cerulein for AEP, the significant cell apoptosis was observed in the pancreatic acinar cell with AEP.
采用蛙皮素腹腔注射造成AEP，发现AEP胰腺存在明显细胞凋亡。
Methods:The ASP model was produced by intravenous infusion of cerulein with the combination of intraductal administration of glycodeoxycholic acid.
方法：用胰胆管内注射甘脱氧胆酸，结合静脉输注蛙皮素方法复制大鼠ASP模型。
Conclusions: Exogenous HGF can attenuate cerulein-induced mild acute pancreatitis in mice. Its mechanism may be related to its effects on arachidonic acid metabolism.
结论：外源性HGF能减轻雨蛙肽诱导的小鼠轻症急性胰腺炎，其机制可能与对花生四烯酸代谢的影响有关。
Methods: Acute pancreatitis model was induced by intraperitoneal injection of cerulein or retrograde infusion of 5% sodium taurocholate into the bilipancreatic duct in SD rats.
方法： 分别采用腹腔注射雨蛙肽和胆胰管逆行注射5%牛磺胆酸钠建立大鼠轻症、重症急性胰腺炎模型。
Methods: Acute pancreatitis model was induced by intraperitoneal injection of cerulein or retrograde infusion of 5% sodium taurocholate into the bilipancreatic duct in SD rats.
方法： 分别采用腹腔注射雨蛙肽和胆胰管逆行注射5%牛磺胆酸钠建立大鼠轻症、重症急性胰腺炎模型。
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